Exacerbation of audiovestibular symptoms in a patient with Ménière's disease and choroidal melanoma

Stefania Barozzi, Daniela Ginocchio, Antonio Cesarani

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We report the case of a man affected by a unilateral Ménière's disease who, after being free from vertigo spells and tinnitus for more than ten years, manifested an exacerbation of symptoms just before the diagnosis of a choroidal melanoma. Melanoma is an aggressive form of cancer derived from neuroectodermal melanocytes. Melanocytes are present in the inner ear where they contribute to the production of endolymphatic potentials and to the maintenance of normal volumes of the inner ear fluids. A possible autoimmune connection between the exacerbation of audiovestibular symptoms and melanoma is discussed.

Original languageEnglish
Pages (from-to)676-677
Number of pages2
JournalAmerican Journal of Otolaryngology - Head and Neck Medicine and Surgery
Issue number5
Publication statusPublished - Sep 1 2014


ASJC Scopus subject areas

  • Otorhinolaryngology
  • Medicine(all)

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