Executive summary of the 2018 KDIGO Hepatitis C in CKD Guideline: welcoming advances in evaluation and management

Michel Jadoul, Marina C. Berenguer, Wahid Doss, Fabrizio Fabrizi, Jacques Izopet, Vivekanand Jha, Nassim Kamar, Bertram L. Kasiske, Ching Lung Lai, José M. Morales, Priti R. Patel, Stanislas Pol, Marcelo O. Silva, Ethan M. Balk, Craig E. Gordon, Amy Earley, Mengyang Di, Paul Martin

Research output: Contribution to journalArticle

Abstract

Infection with the hepatitis C virus (HCV) has adverse liver, kidney, and cardiovascular consequences in patients with chronic kidney disease (CKD), including those on dialysis therapy and in those with a kidney transplant. Since the publication of the original Kidney Disease: Improving Global Outcomes (KDIGO) HCV Guideline in 2008, major advances in HCV management, particularly with the advent of direct-acting antiviral therapies, have now made the cure of HCV possible in CKD patients. In addition, diagnostic techniques have evolved to enable the noninvasive diagnosis of liver fibrosis. Therefore, the Work Group undertook a comprehensive review and update of the KDIGO HCV in CKD Guideline. This Executive Summary highlights key aspects of the guideline recommendations.

Original languageEnglish
Pages (from-to)663-673
Number of pages11
JournalKidney International
Volume94
Issue number4
DOIs
Publication statusPublished - Oct 1 2018

Keywords

  • antivirals
  • chronic kidney disease
  • cryoglobulinemia
  • dialysis
  • direct-acting antivirals
  • glomerular diseases
  • guideline
  • hemodialysis
  • hepatitis C virus
  • infection control
  • KDIGO
  • kidney transplantation
  • liver testing
  • nosocomial transmission
  • screening
  • systematic review

ASJC Scopus subject areas

  • Nephrology

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  • Cite this

    Jadoul, M., Berenguer, M. C., Doss, W., Fabrizi, F., Izopet, J., Jha, V., Kamar, N., Kasiske, B. L., Lai, C. L., Morales, J. M., Patel, P. R., Pol, S., Silva, M. O., Balk, E. M., Gordon, C. E., Earley, A., Di, M., & Martin, P. (2018). Executive summary of the 2018 KDIGO Hepatitis C in CKD Guideline: welcoming advances in evaluation and management. Kidney International, 94(4), 663-673. https://doi.org/10.1016/j.kint.2018.06.011