TY - JOUR
T1 - Exercise
T2 - A "new drug" for elderly patients with chronic heart failure
AU - Antonicelli, Roberto
AU - Spazzafumo, Liana
AU - Scalvini, Simonetta
AU - Olivieri, Fabiola
AU - Matassini, Maria Vittoria
AU - Parati, Gianfranco
AU - Sindaco, Donatella Del
AU - Gallo, Raffaella
AU - Lattanzio, Fabrizia
PY - 2016
Y1 - 2016
N2 - Patients with chronic heart failure (CHF) experience progressive deterioration of functional capacity and quality of life (QoL). This prospective, randomized, controlled trial assesses the effect of exercise training (ET) protocol on functional capacity, rehospitalization, and QoL in CHF patients older than 70 years compared with a control group. A total of 343 elderly patients with stable CHF (age, 76.90±5.67, men, 195, 56.9%) were randomized to ET (TCG, n=170) or usual care (UCG, n=173). The ET protocol involved supervised training sessions for 3 months in the hospital followed by home-telemonitored sessions for 3 months. Assessments, performed at baseline and at 3 and 6 months, included: ECG, resting echocardiography, NTproBNP, 6-minute walk test (6MWT), Minnesota Living with Heart Failure Questionnaire, and comprehensive geriatric assessment with the InterRAI-HC instrument. As compared to UCG, ET patients at 6 months showed: i) significantly increased 6MWT distance (450±83 vs. 290±97 m, p
AB - Patients with chronic heart failure (CHF) experience progressive deterioration of functional capacity and quality of life (QoL). This prospective, randomized, controlled trial assesses the effect of exercise training (ET) protocol on functional capacity, rehospitalization, and QoL in CHF patients older than 70 years compared with a control group. A total of 343 elderly patients with stable CHF (age, 76.90±5.67, men, 195, 56.9%) were randomized to ET (TCG, n=170) or usual care (UCG, n=173). The ET protocol involved supervised training sessions for 3 months in the hospital followed by home-telemonitored sessions for 3 months. Assessments, performed at baseline and at 3 and 6 months, included: ECG, resting echocardiography, NTproBNP, 6-minute walk test (6MWT), Minnesota Living with Heart Failure Questionnaire, and comprehensive geriatric assessment with the InterRAI-HC instrument. As compared to UCG, ET patients at 6 months showed: i) significantly increased 6MWT distance (450±83 vs. 290±97 m, p
KW - 6MWT
KW - Chronic heart failure
KW - Elderly CHF patients
KW - Physical exercise
KW - QoL
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=84976413680&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84976413680&partnerID=8YFLogxK
M3 - Article
VL - 8
SP - 860
EP - 872
JO - Aging
JF - Aging
SN - 0002-0966
IS - 5
ER -