Exercise thallium scintigraphy versus high-dose dipyridamole echocardiography testing for detection of asymptomatic restenosis in patients with positive exercise tests after coronary angioplasty

Salvatore Pirelli, Gian Battista Danzi, Daria Massa, Giacomo Piccalo', Francesco Faletra, Giorgio Cannizzaro, Filippo Sarullo, Eugenio Picano, Claudio De Vita, Luigi Campolo

Research output: Contribution to journalArticlepeer-review

Abstract

The usefulness of high-dose (≤0.84 mg/kg over 10 minutes) dipyridamole echocardiography testing was compared with that of exercise thallium-201 scintigraphy in detecting restenosis (>70% lumen reduction) in 50 asymptomatic patients with ST-segment depression during maximal exercise testing 3 months after successful coronary angioplasty. Dipyridamole echocardiography testing and exercise thallium scintigraphy showed a similar sensitivity (75 vs 83%; p = NS) and specificity (90 vs 84%; p = NS) for the detection of restenoses, which occurred in 12 patients. It is concluded that dipyridamole echocardiography testing is as accurate as exercise thallium testing for the noninvasive detection of severe restenosis in patients with exercise-induced asymptomatic ST-segment depression after successful angioplasty. Furthermore, the site, extent and severity of the thallium perfusion defects during exercise are correlated to those of the dyssynergy during dipyridamole echocardiography.

Original languageEnglish
Pages (from-to)1052-1056
Number of pages5
JournalThe American Journal of Cardiology
Volume71
Issue number12
DOIs
Publication statusPublished - May 1 1993

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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