Exercise training in chronic lung disease: Exercise prescription

A. Patessio, R. Casaburi, C. Prefaut, H. Folgering, C. Donner

Research output: Contribution to journalArticlepeer-review


It is generally acknowledged that training increases exercise tolerance in patients with chronic lung disease. There is recent evidence that the improvement in exercise capacity is accompanied by physiological changes: a) reduction of lactic acidosis, minute ventilation and cardiac frequency for a given work rate, and b) enhanced activity of some mitochondrial enzymes in the trained muscles. Controversy still exists regarding: a) the relative importance of physiological and psychological mechanisms in ameliorating the exercise intolerance; b) whether these mechanisms play different roles in different subgroups of this patient population; and c) the type of training programme which is most appropriate in terms of intensity of work and mode of exercise. Whatever the case there seems to be good justification for exercise therapy being a part of rehabilitation programmes, aimed at improving daily functioning and quality of life of patients with chronic obstructive pulmonary disease.

Original languageEnglish
Pages (from-to)129-146
Number of pages18
JournalEuropean Respiratory Monograph
Issue number6
Publication statusPublished - 1997


  • Chronic obstructive pulmonary disease
  • Exercise training
  • Lactic acidosis
  • Ventilatory limitation

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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