Exercise training in intermittent claudication

R. Gibellini, M. Fanello, A. Ferrari Bardile, M. Salerno, T. Aloi

Research output: Contribution to journalArticle

Abstract

Background. Peripheral arterial occlusive disease (PAOD) at II stage results in a moderate to severe impairment in walking ability. Aim of this study, controlled and randomized, was to evaluate the efficacy of an intensive 4 weeks exercise training in PAOD followed by a six-month period and to analyse the risk factors for atherosclerosis and the site of the lesion for possible predictors of result outcome. Methods. Patients with PAOD were included in the study (ankle/arm ratio ≤ 0.7 and ≤ 0.5 after exercise) with initial claudication distance (ICD) ≤ 200 m and absolute claudication distance (ACD) ≤ 500 m evaluated on a constant-load treadmill test (3 km/hr, 0% slope). Forty patients were randomized (all with antiplatelet therapy): 20 to a supervised walking exercise (mean ICD 121.8 m, ACD 289.7 m) and 20 to a non exercising control group (ICD 111.6 m, ACD 230.1 m). Both groups were tested at 4 weeks (T1) and 6 months (T2). Training group was enrolled in a 4-week supervised training program. Results. In the training group 10% of patients became asymptomatic (> 1000 m). At T1 ICD increased 141% (p <0.001) and ACD was with low-pain-claudication > 1000 m in 50%, at T2 ICD was 200% (p <0.05) with 70% of asymptomatic for ICD and ACD. Control group has a no significant increase of ICD and ACD at T1 and T2. Only arterial hypertension and intermittent claudication severity emerged as negative predictive factors for the results of training. Conclusions. Vascular training produces a significant and lasting improvement in walking distance in PAOD.

Original languageEnglish
Pages (from-to)8-13
Number of pages6
JournalInternational Angiology
Volume19
Issue number1
Publication statusPublished - 2000

Fingerprint

Intermittent Claudication
Arterial Occlusive Diseases
Peripheral Arterial Disease
Exercise
Walking
Control Groups
Exercise Test
Ankle
Blood Vessels
Atherosclerosis
Arm
Demography
Hypertension
Education
Therapeutics

Keywords

  • Arterial occlusive diseases
  • Exercise
  • Intermittent claudication
  • Peripheral vascular diseases

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Gibellini, R., Fanello, M., Ferrari Bardile, A., Salerno, M., & Aloi, T. (2000). Exercise training in intermittent claudication. International Angiology, 19(1), 8-13.

Exercise training in intermittent claudication. / Gibellini, R.; Fanello, M.; Ferrari Bardile, A.; Salerno, M.; Aloi, T.

In: International Angiology, Vol. 19, No. 1, 2000, p. 8-13.

Research output: Contribution to journalArticle

Gibellini, R, Fanello, M, Ferrari Bardile, A, Salerno, M & Aloi, T 2000, 'Exercise training in intermittent claudication', International Angiology, vol. 19, no. 1, pp. 8-13.
Gibellini R, Fanello M, Ferrari Bardile A, Salerno M, Aloi T. Exercise training in intermittent claudication. International Angiology. 2000;19(1):8-13.
Gibellini, R. ; Fanello, M. ; Ferrari Bardile, A. ; Salerno, M. ; Aloi, T. / Exercise training in intermittent claudication. In: International Angiology. 2000 ; Vol. 19, No. 1. pp. 8-13.
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