Exhaled and nasal nitric oxide measurement in the evaluation of chronic cough

Mauro Maniscalco; Salvatore Fuschillo; Carlo Gaudiosi; Alberto De Felice; Michele Martucci; Andrea Motta

doi:10.1016/j.niox.2018.12.005

Exhaled and nasal nitric oxide measurement in the evaluation of chronic cough

Mauro Maniscalco, Salvatore Fuschillo, Carlo Gaudiosi, Alberto De Felice, Michele Martucci, Andrea Motta

Istituti Clinici Scientifici Maugeri Spa – Società Benefit

Research output: Contribution to journal › Review article › peer-review

Abstract

Chronic cough is one of the most common and troublesome nonspecific respiratory symptom for which patients seek a general practitioner and specialist advice. It is conventionally defined as a cough lasting for more than 8 weeks. Exhaled nitric oxide has proven to be a specific biomarker capable to discriminate between differential diagnoses of chronic cough and simultaneously provide information about the response to specific treatment. In this review, we will discuss the potential use of exhaled and nasal nitric oxide in the diagnosis of chronic chough.

Original language	English
Pages (from-to)	19-23
Number of pages	5
Journal	Nitric Oxide - Biology and Chemistry
Volume	83
DOIs	https://doi.org/10.1016/j.niox.2018.12.005
Publication status	Published - Feb 1 2019

Keywords

Asthma/metabolism
Biomarkers/analysis
Breath Tests
Chronic Disease
Cough/metabolism
Exhalation
Humans
Nitric Oxide/analysis
Nose/chemistry

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title = "Exhaled and nasal nitric oxide measurement in the evaluation of chronic cough",

abstract = "Chronic cough is one of the most common and troublesome nonspecific respiratory symptom for which patients seek a general practitioner and specialist advice. It is conventionally defined as a cough lasting for more than 8 weeks. Exhaled nitric oxide has proven to be a specific biomarker capable to discriminate between differential diagnoses of chronic cough and simultaneously provide information about the response to specific treatment. In this review, we will discuss the potential use of exhaled and nasal nitric oxide in the diagnosis of chronic chough.",

keywords = "Asthma/metabolism, Biomarkers/analysis, Breath Tests, Chronic Disease, Cough/metabolism, Exhalation, Humans, Nitric Oxide/analysis, Nose/chemistry",

author = "Mauro Maniscalco and Salvatore Fuschillo and Carlo Gaudiosi and {De Felice}, Alberto and Michele Martucci and Andrea Motta",

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T1 - Exhaled and nasal nitric oxide measurement in the evaluation of chronic cough

AU - Maniscalco, Mauro

AU - Fuschillo, Salvatore

AU - Gaudiosi, Carlo

AU - De Felice, Alberto

AU - Martucci, Michele

AU - Motta, Andrea

PY - 2019/2/1

Y1 - 2019/2/1

N2 - Chronic cough is one of the most common and troublesome nonspecific respiratory symptom for which patients seek a general practitioner and specialist advice. It is conventionally defined as a cough lasting for more than 8 weeks. Exhaled nitric oxide has proven to be a specific biomarker capable to discriminate between differential diagnoses of chronic cough and simultaneously provide information about the response to specific treatment. In this review, we will discuss the potential use of exhaled and nasal nitric oxide in the diagnosis of chronic chough.

AB - Chronic cough is one of the most common and troublesome nonspecific respiratory symptom for which patients seek a general practitioner and specialist advice. It is conventionally defined as a cough lasting for more than 8 weeks. Exhaled nitric oxide has proven to be a specific biomarker capable to discriminate between differential diagnoses of chronic cough and simultaneously provide information about the response to specific treatment. In this review, we will discuss the potential use of exhaled and nasal nitric oxide in the diagnosis of chronic chough.

KW - Asthma/metabolism

KW - Biomarkers/analysis

KW - Breath Tests

KW - Chronic Disease

KW - Cough/metabolism

KW - Exhalation

KW - Humans

KW - Nitric Oxide/analysis

KW - Nose/chemistry

U2 - 10.1016/j.niox.2018.12.005

DO - 10.1016/j.niox.2018.12.005

M3 - Review article

C2 - 30557619

VL - 83

SP - 19

EP - 23

JO - Nitric Oxide - Biology and Chemistry

JF - Nitric Oxide - Biology and Chemistry

SN - 1089-8603

ER -