Exhaled nitric oxide in children with allergic rhinitis andor asthma: A relationship with bronchial hyperreactivity

Giorgio Ciprandi, Maria Angela Tosca, Michele Capasso

Research output: Contribution to journalArticlepeer-review

Abstract

Background. Nowadays, the measure of the fractional concentration of exhaled nitric oxide (FeNO) enables to assess airway inflammation during an office visit and there is international consensus on this testing methodology. The aim of this study was to evaluate whether FeNO measurement is predictable for bronchial hyperreactivity (BHR) in children with allergic rhinitis, asthma, or both. Methods. Two hundred and eighty children with allergic rhinitis, allergic asthma, or both were evaluated. Bronchial function (FEV1 and FEF 25-75), BHR (assessed by methacholine challenge), FeNO, and sensitizations were assessed. Results. Bronchial function, BHR, and FeNO were significantly different in the three groups (p

Original languageEnglish
Pages (from-to)1142-1147
Number of pages6
JournalJournal of Asthma
Volume47
Issue number10
DOIs
Publication statusPublished - Dec 2010

Keywords

  • allergic rhinitis
  • asthma
  • bronchial hyperreactivity
  • children
  • nitric oxide

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Immunology and Allergy
  • Pediatrics, Perinatology, and Child Health

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