Exhaled nitric oxide in children with allergic rhinitis andor asthma: A relationship with bronchial hyperreactivity

Giorgio Ciprandi; Maria Angela Tosca; Michele Capasso

doi:10.3109/02770903.2010.527026

Exhaled nitric oxide in children with allergic rhinitis andor asthma: A relationship with bronchial hyperreactivity

Giorgio Ciprandi, Maria Angela Tosca, Michele Capasso

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article › peer-review

Abstract

Background. Nowadays, the measure of the fractional concentration of exhaled nitric oxide (FeNO) enables to assess airway inflammation during an office visit and there is international consensus on this testing methodology. The aim of this study was to evaluate whether FeNO measurement is predictable for bronchial hyperreactivity (BHR) in children with allergic rhinitis, asthma, or both. Methods. Two hundred and eighty children with allergic rhinitis, allergic asthma, or both were evaluated. Bronchial function (FEV1 and FEF _25-75), BHR (assessed by methacholine challenge), FeNO, and sensitizations were assessed. Results. Bronchial function, BHR, and FeNO were significantly different in the three groups (p

Original language	English
Pages (from-to)	1142-1147
Number of pages	6
Journal	Journal of Asthma
Volume	47
Issue number	10
DOIs	https://doi.org/10.3109/02770903.2010.527026
Publication status	Published - Dec 2010

Keywords

allergic rhinitis
asthma
bronchial hyperreactivity
children
nitric oxide

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Immunology and Allergy
Pediatrics, Perinatology, and Child Health

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AU - Capasso, Michele

PY - 2010/12

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