Expanding indications for the treatment of pulmonary artery stenosis in children by using cutting balloon angioplasty

Gianfranco Butera, La Torre Marco Antonio, Chessa Massimo, Carminati Mario

Research output: Contribution to journalArticlepeer-review


Objectives: To evaluate the role of cutting balloon angioplasty in children with pulmonary artery stenosis. Background: Pulmonary artery stenoses can be either congenital or secondary to postoperative scar formation. Isolated multiple small-vessel pulmonary artery stenoses are very rare. No surgical procedures for their treatment are currently available. Methods: We report on four patients in whom standard and high-pressure balloon angioplasty had failed. Three of the four (2.5-, 3-, and 3.5-years-old; two girls) had isolated multiple peripheral pulmonary artery stenosis. The fourth patient was an 11-month-old girl (8 kg) with tetralogy of Fallet and hypoplastic pulmonary artery branches treated with the implantation of two stents in the pulmonary arteries. During the follow-up this patient developed severe intrastent restenosis and showed severely hypoplasic distal left pulmonary artery. Results: We treated 11 vessels. The mean vessel diameter increased by 81% (P <0.0001) and RV/LV pressure ratio decreased from 1.15 to 0.75 (P = 0.05). Patient treated for intrastent restenosis underwent successful complete tetralogy of Fallot repair. None of the patients suffered procedure-related complications. At a median follow-up of 18 months, results were stable and no late complications had occurred. Conclusions: Cutting balloon angioplasty is a promising technique for the treatment of highly challenging pathologies such as small vessel pulmonary artery stenoses and intrastent restenosis.

Original languageEnglish
Pages (from-to)460-465
Number of pages6
JournalCatheterization and Cardiovascular Interventions
Issue number3
Publication statusPublished - Mar 2006


  • Cardiac catheterization
  • Children
  • Heart
  • Treatment

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging


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