Expectancy modulates pupil size both during endogenous orienting and during re-orienting of spatial attention: A study with isoluminant stimuli

Stefano Lasaponara, Gianfranco Fortunato, Alessio Dragone, Michele Pellegrino, Fabio Marson, Massimo Silvetti, Mario Pinto, Marianna D'Onofrio, Fabrizio Doricchi

Research output: Contribution to journalArticle

Abstract

We have recently demonstrated that when endogenous orienting of spatial attention is guided by central directional cues that reliably predict the position of lateral targets. Pupil Dilation (PDil) is higher as compared with directional cues that do not predict target position. These findings were interpreted as reflecting different levels of Locus Coeruleus-Noradrenergic activity during endogenous orienting. In contrast to this, we were not able to highlight reliable differences between PDil responses to infrequent invalid targets that are associated with predictive cues and frequent invalid targets that are associated with non-predictive ones. These null findings might have been due to the spurious influence of transitory changes in luminance at the moment of target presentation or to the short time window used for the analysis of target-related changes in PDil. Here, we re-explored cue- and target-related changes in PDil using cue and target stimuli that were kept isoluminant to their background and long lasting cue and target periods for data recording and analysis. We fully replicate our previous cue-related results and, in addition, we demonstrate that infrequent invalid targets in the predictive experimental condition evoke larger PDil as compared with frequent ones. Analyses with Linear Mixed Models highlighted that both during the cue and target period, higher levels of PDil were associated with slower reaction times. These findings confirm that PDil is a reliable marker of the expectancy components of endogenous cue-related and exogenous target-related orienting of spatial attention.

Original languageEnglish
JournalEuropean Journal of Neuroscience
DOIs
Publication statusPublished - Jan 1 2019

Fingerprint

Pupil
Cues
Dilatation
Locus Coeruleus
Reaction Time
Linear Models

Keywords

  • expectancy
  • predictive coding
  • pupil dilation
  • spatial attention

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Expectancy modulates pupil size both during endogenous orienting and during re-orienting of spatial attention : A study with isoluminant stimuli. / Lasaponara, Stefano; Fortunato, Gianfranco; Dragone, Alessio; Pellegrino, Michele; Marson, Fabio; Silvetti, Massimo; Pinto, Mario; D'Onofrio, Marianna; Doricchi, Fabrizio.

In: European Journal of Neuroscience, 01.01.2019.

Research output: Contribution to journalArticle

Lasaponara, Stefano ; Fortunato, Gianfranco ; Dragone, Alessio ; Pellegrino, Michele ; Marson, Fabio ; Silvetti, Massimo ; Pinto, Mario ; D'Onofrio, Marianna ; Doricchi, Fabrizio. / Expectancy modulates pupil size both during endogenous orienting and during re-orienting of spatial attention : A study with isoluminant stimuli. In: European Journal of Neuroscience. 2019.
@article{8c8ee123d7104d838b070fe0ad53f1d3,
title = "Expectancy modulates pupil size both during endogenous orienting and during re-orienting of spatial attention: A study with isoluminant stimuli",
abstract = "We have recently demonstrated that when endogenous orienting of spatial attention is guided by central directional cues that reliably predict the position of lateral targets. Pupil Dilation (PDil) is higher as compared with directional cues that do not predict target position. These findings were interpreted as reflecting different levels of Locus Coeruleus-Noradrenergic activity during endogenous orienting. In contrast to this, we were not able to highlight reliable differences between PDil responses to infrequent invalid targets that are associated with predictive cues and frequent invalid targets that are associated with non-predictive ones. These null findings might have been due to the spurious influence of transitory changes in luminance at the moment of target presentation or to the short time window used for the analysis of target-related changes in PDil. Here, we re-explored cue- and target-related changes in PDil using cue and target stimuli that were kept isoluminant to their background and long lasting cue and target periods for data recording and analysis. We fully replicate our previous cue-related results and, in addition, we demonstrate that infrequent invalid targets in the predictive experimental condition evoke larger PDil as compared with frequent ones. Analyses with Linear Mixed Models highlighted that both during the cue and target period, higher levels of PDil were associated with slower reaction times. These findings confirm that PDil is a reliable marker of the expectancy components of endogenous cue-related and exogenous target-related orienting of spatial attention.",
keywords = "expectancy, predictive coding, pupil dilation, spatial attention",
author = "Stefano Lasaponara and Gianfranco Fortunato and Alessio Dragone and Michele Pellegrino and Fabio Marson and Massimo Silvetti and Mario Pinto and Marianna D'Onofrio and Fabrizio Doricchi",
year = "2019",
month = "1",
day = "1",
doi = "10.1111/ejn.14391",
language = "English",
journal = "European Journal of Neuroscience",
issn = "0953-816X",
publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - Expectancy modulates pupil size both during endogenous orienting and during re-orienting of spatial attention

T2 - A study with isoluminant stimuli

AU - Lasaponara, Stefano

AU - Fortunato, Gianfranco

AU - Dragone, Alessio

AU - Pellegrino, Michele

AU - Marson, Fabio

AU - Silvetti, Massimo

AU - Pinto, Mario

AU - D'Onofrio, Marianna

AU - Doricchi, Fabrizio

PY - 2019/1/1

Y1 - 2019/1/1

N2 - We have recently demonstrated that when endogenous orienting of spatial attention is guided by central directional cues that reliably predict the position of lateral targets. Pupil Dilation (PDil) is higher as compared with directional cues that do not predict target position. These findings were interpreted as reflecting different levels of Locus Coeruleus-Noradrenergic activity during endogenous orienting. In contrast to this, we were not able to highlight reliable differences between PDil responses to infrequent invalid targets that are associated with predictive cues and frequent invalid targets that are associated with non-predictive ones. These null findings might have been due to the spurious influence of transitory changes in luminance at the moment of target presentation or to the short time window used for the analysis of target-related changes in PDil. Here, we re-explored cue- and target-related changes in PDil using cue and target stimuli that were kept isoluminant to their background and long lasting cue and target periods for data recording and analysis. We fully replicate our previous cue-related results and, in addition, we demonstrate that infrequent invalid targets in the predictive experimental condition evoke larger PDil as compared with frequent ones. Analyses with Linear Mixed Models highlighted that both during the cue and target period, higher levels of PDil were associated with slower reaction times. These findings confirm that PDil is a reliable marker of the expectancy components of endogenous cue-related and exogenous target-related orienting of spatial attention.

AB - We have recently demonstrated that when endogenous orienting of spatial attention is guided by central directional cues that reliably predict the position of lateral targets. Pupil Dilation (PDil) is higher as compared with directional cues that do not predict target position. These findings were interpreted as reflecting different levels of Locus Coeruleus-Noradrenergic activity during endogenous orienting. In contrast to this, we were not able to highlight reliable differences between PDil responses to infrequent invalid targets that are associated with predictive cues and frequent invalid targets that are associated with non-predictive ones. These null findings might have been due to the spurious influence of transitory changes in luminance at the moment of target presentation or to the short time window used for the analysis of target-related changes in PDil. Here, we re-explored cue- and target-related changes in PDil using cue and target stimuli that were kept isoluminant to their background and long lasting cue and target periods for data recording and analysis. We fully replicate our previous cue-related results and, in addition, we demonstrate that infrequent invalid targets in the predictive experimental condition evoke larger PDil as compared with frequent ones. Analyses with Linear Mixed Models highlighted that both during the cue and target period, higher levels of PDil were associated with slower reaction times. These findings confirm that PDil is a reliable marker of the expectancy components of endogenous cue-related and exogenous target-related orienting of spatial attention.

KW - expectancy

KW - predictive coding

KW - pupil dilation

KW - spatial attention

UR - http://www.scopus.com/inward/record.url?scp=85063676479&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85063676479&partnerID=8YFLogxK

U2 - 10.1111/ejn.14391

DO - 10.1111/ejn.14391

M3 - Article

AN - SCOPUS:85063676479

JO - European Journal of Neuroscience

JF - European Journal of Neuroscience

SN - 0953-816X

ER -