Experiences with immunomodulant agents in HIV infections

A. Lazzarin, W. Barcellini, C. Uberti Foppa, M. O. Borghi, F. Franzetti, P. Cinque, M. Moroni

Research output: Contribution to journalArticle

Abstract

Drug addicts with persistent generalized lymphadenopathy displayed the following immunological abnormalities: An inverted OKT4/OKT8 ratio, a depressed in vitro blastogenetic response to phytohemagglutinin and pokeweed mitogen (PWM), a reduced ability of PMNL to phagocytose and kill Candida albicans spores and to migrate in presence of a chemotactic factor. Thymopentin treatment (50 mg s.c. 3 times/week for 3 weeks and repeated after 3 months at 50 mg s.c. once a week for 3 months) improved OKT4+ lymphocytes (p

Original languageEnglish
Pages (from-to)84-90
Number of pages7
JournalActa Haematologica
Volume78
DOIs
Publication statusPublished - 1987

Keywords

  • Candida albicans test
  • HIV infection
  • Thymopentin

ASJC Scopus subject areas

  • Hematology

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