Experimental and therapeutical effects of sulpiride on the gastric and duodenal ulcer

M. Bortolotti, A. Baruzzi, L. Barbara

Research output: Contribution to journalArticle

Abstract

Sulpiride (N[1 ethyl 2 pyrrolidinyl methyl] 2 methoxy 5 sulfamoylbenzamide) represents a further improvement in these drugs, since, while having antidepressant, antipsychotic, antiemetic and uninhibiting properties, it does not produce any drowsiness nor does it provoke a peripheral block of the autonomic nervous system. These characteristics induced several research workers to carry out studies not only in psychiatry, but also in psychosomatic medicine, and in particular in the peptic ulcer. This research on the effect of sulpiride on the ulcer was divided into two separate parts: a clinical therapeutic study to examine the antiulcer effectiveness of the drug and an experimental study to investigate the mechanism of the drug action on the gastric function; the results in 33 patients with peptic ulcer are discussed.

Original languageEnglish
Pages (from-to)33-40
Number of pages8
JournalMedicina Psicosomatica
Volume20
Issue number1
Publication statusPublished - 1975

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Sulpiride
Stomach Ulcer
Duodenal Ulcer
Peptic Ulcer
Pharmaceutical Preparations
Psychosomatic Medicine
Antiemetics
Sleep Stages
Autonomic Nervous System
Research
Antidepressive Agents
Antipsychotic Agents
Ulcer
Psychiatry
Stomach
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Experimental and therapeutical effects of sulpiride on the gastric and duodenal ulcer. / Bortolotti, M.; Baruzzi, A.; Barbara, L.

In: Medicina Psicosomatica, Vol. 20, No. 1, 1975, p. 33-40.

Research output: Contribution to journalArticle

Bortolotti, M, Baruzzi, A & Barbara, L 1975, 'Experimental and therapeutical effects of sulpiride on the gastric and duodenal ulcer', Medicina Psicosomatica, vol. 20, no. 1, pp. 33-40.
Bortolotti, M. ; Baruzzi, A. ; Barbara, L. / Experimental and therapeutical effects of sulpiride on the gastric and duodenal ulcer. In: Medicina Psicosomatica. 1975 ; Vol. 20, No. 1. pp. 33-40.
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