Experimental evaluation of the safety and biocompatibility of a new antireflux prosthesis

H. Feussner, L. Bonavina, M. Collard, J. Holste, S. Freys, Ö P. Horváth, T. Rüdiger, H. J. Stein, K. H. Fuchs

Research output: Contribution to journalArticlepeer-review

Abstract

Previous studies have shown that encircling of the esophagogastric junction by a semiabsorbable scarf effectively prevents gastroesophageal reflux. The present study was performed to assess the long-term safety and biocompatibility of this type of scarf. The semiabsorbable scarf was implanted into 20 dogs either laparoscopically or via laparotomy. Pre- and post-operatively, contrast radiography, esophageal manometry, and upper gastrointestinal endoscopy were performed. No cases of perforation, stricture formation or other adverse effects were found after 1 and 2 years. It is concluded that the new type of scarf is without any adverse side-effects. Functional evaluation in reflux patients appears to be warranted.

Original languageEnglish
Pages (from-to)234-239
Number of pages6
JournalDiseases of the Esophagus
Volume13
Issue number3
DOIs
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Gastroenterology

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