Expert consensus document from the European Society of Cardiology on catheter-based renal denervation

Felix Mahfoud, Thomas Felix Lüscher, Bert Andersson, Iris Baumgartner, Renata Cifkova, Carlo DiMario, Pieter Doevendans, Robert Fagard, Jean Fajadet, Michel Komajda, Thierry LeFèvre, Chaim Lotan, Horst Sievert, Massimo Volpe, Petr Widimsky, William Wijns, Bryan Williams, Stephan Windecker, Adam Witkowski, Thomas ZellerMichael Böhm

Research output: Contribution to journalArticlepeer-review


Current evidence from the available clinical trials strongly support the notion that catheter-based radiofrequency ablation of renal nerves reduces blood pressure and improves blood pressure control in patients with drug-treated resistant hypertension, with data now extending out to 36 months. Accordingly, renal denervation can be considered as a therapeutic option in patients with resistant hypertension, whose blood pressure cannot be controlled by a combination of lifestyle modification and pharmacological therapy according to current guidelines. The fact that renal denervation also reduces whole-bodysympathetic nerve activity suggests that this therapy may also be beneficial in other clinical states characterized by sympathetic nervous system activation-this may ultimately lead to new indications.

Original languageEnglish
Pages (from-to)2149-2157
Number of pages9
JournalEuropean Heart Journal
Issue number28
Publication statusPublished - Jul 21 2013

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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