Exploratory Decision-Tree Modeling of Data from the Randomized REACTT Trial of Tadalafil Versus Placebo to Predict Recovery of Erectile Function After Bilateral Nerve-Sparing Radical Prostatectomy

Francesco Montorsi, Matthias Oelke, Carsten Henneges, Gerald Brock, Andrea Salonia, Gianluca d'Anzeo, Andrea Rossi, John P. Mulhall, Hartwig Büttner

Research output: Contribution to journalArticle

Abstract

Background Understanding predictors for the recovery of erectile function (EF) after nerve-sparing radical prostatectomy (nsRP) might help clinicians and patients in preoperative counseling and expectation management of EF rehabilitation strategies. Objective To describe the effect of potential predictors on EF recovery after nsRP by post hoc decision-tree modeling of data from A Study of Tadalafil After Radical Prostatectomy (REACTT). Design, setting, and participants Randomized double-blind double-dummy placebo-controlled trial in 423 men aged
Original languageEnglish
Pages (from-to)529 - 537
Number of pages9
JournalEuropean Urology
Volume70
Issue number3
DOIs
Publication statusPublished - Sep 1 2016

Keywords

  • Clinical trials
  • Decision-tree analysis
  • Erectile dysfunction
  • Nerve-sparing radical prostatectomy
  • Phosphodiesterase type 5 inhibitors
  • Predictors
  • Prostate cancer
  • Rehabilitation
  • Tadalafil

ASJC Scopus subject areas

  • Urology

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