Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 635-639 |
| Number of pages | 5 |
| Journal | Digestive and Liver Disease |
| Volume | 50 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 1 2018 |
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Keywords
- Gut microbiota
- Metabolic syndrome
- Molecular mimicry
- Neurologic disorders
Cite this
Exploring Bacteroidetes: Metabolic key points and immunological tricks of our gut commensals. / Gibiino, Giulia; Lopetuso, Loris Riccardo; Scaldaferri, Franco; Rizzatti, Gianenrico; Binda, Cecilia; Gasbarrini, Antonio.
In: Digestive and Liver Disease, Vol. 50, No. 7, 01.07.2018, p. 635-639.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Exploring Bacteroidetes: Metabolic key points and immunological tricks of our gut commensals
AU - Gibiino, Giulia
AU - Lopetuso, Loris Riccardo
AU - Scaldaferri, Franco
AU - Rizzatti, Gianenrico
AU - Binda, Cecilia
AU - Gasbarrini, Antonio
PY - 2018/7/1
Y1 - 2018/7/1
N2 - © 2018 Bacteroidetes are the largest phylum of Gram-negative bacteria inhabiting our gastrointestinal tract and are considered the leading players of the healthy state and sophisticated homeostasis safeguarded by gut microbiota. Furthermore, specific roles have been attributed to some Bacteroidetes genera in the development of immune dysregulation, systemic disease such as metabolic syndrome and also neurological disorders. Glycoproteins secretion, short fatty acids imbalance, toxins production and molecular mimicry are only a part of the functions exerted by these commensals interacting with the host. The aim of this review is to summarize the current knowledge on the recognized role of Bacteroidetes in physiological functions and pathological networks in order to define the needs for future research and clarify the potential role for targeted microbial therapies.
AB - © 2018 Bacteroidetes are the largest phylum of Gram-negative bacteria inhabiting our gastrointestinal tract and are considered the leading players of the healthy state and sophisticated homeostasis safeguarded by gut microbiota. Furthermore, specific roles have been attributed to some Bacteroidetes genera in the development of immune dysregulation, systemic disease such as metabolic syndrome and also neurological disorders. Glycoproteins secretion, short fatty acids imbalance, toxins production and molecular mimicry are only a part of the functions exerted by these commensals interacting with the host. The aim of this review is to summarize the current knowledge on the recognized role of Bacteroidetes in physiological functions and pathological networks in order to define the needs for future research and clarify the potential role for targeted microbial therapies.
KW - Gut microbiota
KW - Metabolic syndrome
KW - Molecular mimicry
KW - Neurologic disorders
UR - http://www.scopus.com/inward/record.url?scp=85045113784&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85045113784&partnerID=8YFLogxK
U2 - 10.1016/j.dld.2018.03.016
DO - 10.1016/j.dld.2018.03.016
M3 - Review article
C2 - 29650468
AN - SCOPUS:85045113784
VL - 50
SP - 635
EP - 639
JO - Digestive and Liver Disease
JF - Digestive and Liver Disease
SN - 1590-8658
IS - 7
ER -