Exploring the relationship between endometriomas and infertility

Nicola Berlanda, Daniela Alberico, Giussy Barbara, Maria Pina Frattaruolo, Paolo Vercellini

Research output: Contribution to journalArticlepeer-review


Several clinical and epidemiological studies demonstrated an association between endometriosis and infertility. A role in the genesis of infertility may be played by endometriomas, which may interfere with ovulation or damage ovarian tissue. Unlike peritoneal implants, the availability of an accurate noninvasive sonographic diagnosis facilitates the investigation of endometrioma associated infertility. The laparoscopic excision of an endometrioma relieves the ovary from the damage caused by the cyst itself, which may be progressive over time, but at the same time is associated with a detrimental effect on ovarian reserve and with high rates of postoperative endometrioma recurrence. Therefore, the management of endometrioma-related infertility should not be based upon surgery alone, but upon a combination of surgery, with a refinement of the operating technique, long-term oral contraceptive, in vitro fertilization and oocyte cryopreservation.

Original languageEnglish
Pages (from-to)127-135
Number of pages9
JournalWomen's health (London, England)
Issue number2
Publication statusPublished - Mar 1 2015


  • female infertility
  • in vitro fertilization
  • laparoscopic surgery
  • ovarian endometriomas
  • ovarian reserve

ASJC Scopus subject areas

  • Medicine(all)


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