Exposome informatics: Considerations for the design of future biomedical research information systems

Fernando Martin Sanchez, Kathleen Gray, Riccardo Bellazzi, Guillermo Lopez-Campos

Research output: Contribution to journalArticle

Abstract

The environment's contribution to health has been conceptualized as the exposome. Biomedical research interest in environmental exposures as a determinant of physiopathological processes is rising as such data increasingly become available. The panoply of miniaturized sensing devices now accessible and affordable for individuals to use to monitor a widening range of parameters opens up a new world of research data. Biomedical informatics (BMI) must provide a coherent framework for dealing with multi-scale population data including the phenome, the genome, the exposome, and their interconnections. The combination of these more continuous, comprehensive, and personalized data sources requires new research and development approaches to data management, analysis, and visualization. This article analyzes the implications of a new paradigm for the discipline of BMI, one that recognizes genome, phenome, and exposome data and their intricate interactions as the basis for biomedical research now and for clinical care in the near future.

Original languageEnglish
Pages (from-to)386-390
Number of pages5
JournalJournal of the American Medical Informatics Association
Volume21
Issue number3
DOIs
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Health Informatics
  • Medicine(all)

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