Exposure to 50Hz electromagnetic field raises the levels of the anti-apoptotic protein BAG3 in melanoma cells

Anna Basile, Rosario Zeppa, Nicola Pasquino, Claudio Arra, Massimo Ammirante, Michelina Festa, Antonio Barbieri, Aldo Giudice, Maria Pascale, Maria Caterina Turco, Alessandra Rosati

Research output: Contribution to journalArticlepeer-review

Abstract

The expression of the anti-apoptotic protein BAG3 is induced in several cell types by exposure to high temperature, oxidants, and other stressful agents. We investigated whether exposure to 50Hz electromagnetic fields raised BAG3 levels in the human melanoma cell line M14, in vitro and in orthotopic xenografts. Exposure of cultured cells or xenografts for 6h or 4 weeks, respectively, produced a significant (P

Original languageEnglish
Pages (from-to)2901-2907
Number of pages7
JournalJournal of Cellular Physiology
Volume226
Issue number11
DOIs
Publication statusPublished - Nov 2011

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology
  • Physiology

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