TY - JOUR
T1 - Exposure to benzene and risk of breast cancer among shoe factory workers in Italy
AU - Costantini, Adele Seniori
AU - Gorini, Giuseppe
AU - Consonni, Dario
AU - Miligi, Lucia
AU - Giovannetti, Lucia
AU - Quinn, Margaret
PY - 2009/1
Y1 - 2009/1
N2 - Alms and background. Evidence of the association between leukemia and benzene exposure has been provided by several epidemiological studies. An increased risk of breast cancer among women exposed to benzene has also been suggested. The aim of this study was to analyze breast cancer risk in a cohort of 1,002 women exposed to benzene in a shoe factory in Florence, Italy, where an excess of leukemia in men was reported. Methods. The cohort of women at work on January 1st, 1950, was followed from 1950 to 2003 for mortality and from 1985 to 2000 for incidence of breast cancer. For a sub- cohort of 797 women, cumulative exposure to benzene was available. Results. Standardized mortality ratios were obtained for the 797 women for whom in formation on cumulative exposure was available. For those with 40 ppm- year and ≥30 year latency period category, the standardized mortality ratio was 166.0 (95% CI, 62.3-442.2, based on 4 deaths). The standardized incidence ratio for women with a latency period 40 ppm-years and a latency period
AB - Alms and background. Evidence of the association between leukemia and benzene exposure has been provided by several epidemiological studies. An increased risk of breast cancer among women exposed to benzene has also been suggested. The aim of this study was to analyze breast cancer risk in a cohort of 1,002 women exposed to benzene in a shoe factory in Florence, Italy, where an excess of leukemia in men was reported. Methods. The cohort of women at work on January 1st, 1950, was followed from 1950 to 2003 for mortality and from 1985 to 2000 for incidence of breast cancer. For a sub- cohort of 797 women, cumulative exposure to benzene was available. Results. Standardized mortality ratios were obtained for the 797 women for whom in formation on cumulative exposure was available. For those with 40 ppm- year and ≥30 year latency period category, the standardized mortality ratio was 166.0 (95% CI, 62.3-442.2, based on 4 deaths). The standardized incidence ratio for women with a latency period 40 ppm-years and a latency period
KW - Benzene
KW - Breast cancer
KW - Shoe worker
UR - http://www.scopus.com/inward/record.url?scp=63449120361&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=63449120361&partnerID=8YFLogxK
M3 - Article
C2 - 19366049
AN - SCOPUS:63449120361
VL - 95
SP - 8
EP - 12
JO - Tumori
JF - Tumori
SN - 0300-8916
IS - 1
ER -