Exposure to ozone inhibits isolation‐induced aggressive behavior of adult CD‐1 male mice

S. Petruzzi, M. Fiore, G. Dell'Omo, E. Alleva

Research output: Contribution to journalArticlepeer-review

Abstract

Continuous exposure to ozone (O3, 1.2 ppm) in adult CD‐1 male mice for 20 consecutive days markedly influenced a number of items of aggressive behavior induced by 59 days of individual housing. The behavior of mice was videotaped on days 1, 3, and 5 of five consecutive daily encounters (10 min each; isolation days 55, 57, and 59). Ozone exposure caused an abatement of aggressive behavior and enhanced fear‐associated displays shown by a significant decrease in the frequency of attacking and digging and an increase in freezing. Moreover, O3 induced a decrease of time spent in attacking and exploration/activity. Nonexposed animals exhibited a day‐dependent increase in self‐grooming frequency which was not observed in O3 mice; by contrast, freezing was higher in O3 mice on day 5 of the test. Data suggest that O3 exposure produces a remarkable reduction of mouse aggression, indirectly confirming previous findings on physical and neurobehavioral effects of O3. © 1995 Wiley‐Liss, Inc.

Original languageEnglish
Pages (from-to)387-396
Number of pages10
JournalAggressive Behavior
Volume21
Issue number5
DOIs
Publication statusPublished - 1995

Keywords

  • aggressive behavior
  • fear‐associated displays
  • mouse
  • ozone

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Arts and Humanities (miscellaneous)
  • Psychology(all)

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