Exposure to vehicular traffic is associated to a higher risk of hospitalization for bronchiolitis during the first year of life

Marcello Lanari, S. Vandini, Federica Prinelli, Fulvio Adorni, Simona Gabriella Di Santo, Michela Silvestri, Massimo Musicco, Faldella Giacomo, Spinelli Marica, Corsello Giovanni, Gabriele Bruna, Boldrini Antonio, Vuerich Marco, Del Vecchio Antonio, Bertino Enrico, Coscia Alessandra, Fanos Vassilios, Puddu Melania, Gargano Giancarlo, Braibanti SilviaOrfeo Luigi, De Luca Maria Gabriella, Paolillo Piermichele, Fabiano Adele, Barberi Ignazio, Arco Alessandro, Bonomi Alberto, Dallagnola Alberto, Di Fabio Sandra, Bottau Paolo, La Forgia Nicola, Macagno Francesco, Ellero Serena, Magaldi Rosario, Rinaldi Matteo, Memo Luigi, Nicolini Giangiacomo, Ngalikpima Catherine Jessica, Nosari Norberto, Sarnelli Paolo, Parmigiani Stefano, Agosti Massimo, Negri Carlo, De Curtis Mario, Natale Fabio, Aurilia Claudia, Romagnoli Costantino

Research output: Contribution to journalArticle

Abstract

BACKGROUND: The most common cause of hospitalization for children younger than age one is bronchiolitis. Several prenatal and environmental risk factors may affect the incidence of hospitalization for bronchiolitis. The aim of this study was to investigate the relation between exposure to vehicular traffic and the incidence of hospitalization for bronchiolitis in children during their first year of life in Italy. METHODS: A multicenter prospective birth cohort study, where equal numbers of newborns of 33-34, 35-37 and .38 wGA were recruited at birth (1814 children) in 30 Italian neonatology units. Two interviewer-administered questionnaires were used to collect data. The first interview was carried out at the end of the Italian epidemic season. The second interview was carried out when the child was one year old. Data on possible prenatal, perinatal, and postnatal/environmental risk factors and on vehicular traffic density in the zone of residence were collected. On each interview, parents were also asked about any hospitalizations of the child. The outcome measure was the hospitalization for bronchiolitis (International Health Service ICD-9 code 466). RESULTS: Univariate analysis demonstrated that exposure to air pollution due to vehicular traffic, was significantly associated with an increased risk of hospitalization for bronchiolitis. The adjusted risk from logistic regression model confirmed that children exposed to air pollution due to vehicular traffic were at increased risk of hospitalization for bronchiolitis. CONCLUSIONS: Exposure to air pollution due to vehicular traffic may increase the risk of hospitalization for bronchiolitis in the first year of life.

Original languageEnglish
Pages (from-to)391-397
Number of pages7
JournalMinerva Pediatrica
Volume68
Issue number6
Publication statusPublished - Dec 1 2016

Keywords

  • Air pollution
  • Bronchiolitis
  • Child
  • Hospitalization
  • Respiratory syncytial viruses
  • Risk factors

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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  • Cite this

    Lanari, M., Vandini, S., Prinelli, F., Adorni, F., Di Santo, S. G., Silvestri, M., Musicco, M., Giacomo, F., Marica, S., Giovanni, C., Bruna, G., Antonio, B., Marco, V., Antonio, D. V., Enrico, B., Alessandra, C., Vassilios, F., Melania, P., Giancarlo, G., ... Costantino, R. (2016). Exposure to vehicular traffic is associated to a higher risk of hospitalization for bronchiolitis during the first year of life. Minerva Pediatrica, 68(6), 391-397.