Expression of leucocyte integrins in B-cell chronic lymphoproliferative disorders

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Abstract

Leucocyte integrins are cell adhesion molecules (CAMs) involved in the regulation of lymphocyte trafficking. We performed a flow cytometric analysis of peripheral blood (PB) from 68 patients suffering from several B-cell chronic lymphoproliferative disorders (CLDs) in leukaemic phase, in order to get more informations on the expression of CD11a, CD11b, CD11c and CD18 molecules by malignant B-cells. A defective expression of CD18/CD11a receptorial complex, compared to normal controls, was found (p

Original languageEnglish
Pages (from-to)74-77
Number of pages4
JournalTrasfusione del Sangue
Volume45
Issue number2
Publication statusPublished - 2000

Keywords

  • Cell adhesion molecules
  • Chronic leukaemias
  • Non-Hodgkin's lymphoma

ASJC Scopus subject areas

  • Hematology
  • Immunology and Allergy

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