Expression of neural-tissue markers (S-100 protein and Leu-7 antigen) by sweat gland tumors of the skin. An immunohistochemical study

J. Kanitakis, G. Zambruno, J. Viac, H. Panzini, J. Thivolet

Research output: Contribution to journalArticlepeer-review

Abstract

The expression of two immunohistochemical markers of neural tissue and of cutaneous sweat glands (S-100 protein and Leu-7 antigen) was studied in a group of cutaneous epithelial, mostly glandular, tumors. These antigens were detected only on sweat gland neoplasms showing both types (eccrine and apocrine) of differentiation. These results suggest that antibodies to S-100 protein and to Leu-7 antigen have a limited value in the distinction between eccrine and apocrine tumours, but they may serve as a useful adjunct for the confirmation of the glandular differentiation of cutaneous epithelial tumors.

Original languageEnglish
Pages (from-to)187-191
Number of pages5
JournalJournal of the American Academy of Dermatology
Volume17
Issue number2 I
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Dermatology

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