Abstract
The expression of two immunohistochemical markers of neural tissue and of cutaneous sweat glands (S-100 protein and Leu-7 antigen) was studied in a group of cutaneous epithelial, mostly glandular, tumors. These antigens were detected only on sweat gland neoplasms showing both types (eccrine and apocrine) of differentiation. These results suggest that antibodies to S-100 protein and to Leu-7 antigen have a limited value in the distinction between eccrine and apocrine tumours, but they may serve as a useful adjunct for the confirmation of the glandular differentiation of cutaneous epithelial tumors.
Original language | English |
---|---|
Pages (from-to) | 187-191 |
Number of pages | 5 |
Journal | Journal of the American Academy of Dermatology |
Volume | 17 |
Issue number | 2 I |
Publication status | Published - 1987 |
ASJC Scopus subject areas
- Dermatology