Expression of SpanX mRNA in testicular germ cell tumors.

Michele Salemi, Aldo E. Calogero, Paolo Bosco, Roberto Castiglione, Sandro La Vignera, Eugenia Borgione, Giancarlo Rappazzo, Enzo Vicari

Research output: Contribution to journalArticlepeer-review


The function of SpanX proteins is unknown, evidence is accumulating to suggest their involvement in tumorigenesis. A locus in Xq27, where the SpanX gene family is located, has been associated with testicular germ cell tumor (TGCT) onset. Therefore, we evaluated the presence of SpanX mRNA in six TGCT cases by RT-PCR. The results showed that SpanX mRNA is present in TGCT, confirming transcriptional activity of these genes in such tumors.

Original languageEnglish
Pages (from-to)87-90
Number of pages4
JournalHuman Cell
Issue number3
Publication statusPublished - Aug 2006

ASJC Scopus subject areas

  • Cancer Research
  • Cell Biology


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