Expression of the mRNA for the ligand of C-kit in mouse sertoli cells

Pellegrino Rossi, Cristina Albanesi, Paola Grimaldi, Raffaele Geremia

Research output: Contribution to journalArticlepeer-review

Abstract

The expression of the mRNA for SLF (the c-kit ligand), a product of the "steel" locus, has been investigated in postnatal mouse testis and homogeneous populations of testicular cells. The message was found expressed in postnatal mouse testis but not in germ cells. Studies on primary mouse Sertoli cell cultures from 18 day old mice show that Sertoli cells are the site of SLF mRNA expression in the seminiferous tubules. Treatment of Sertoli cell cultures with cAMP analogs led to a significant increase in the SLF mRNA levels.

Original languageEnglish
Pages (from-to)910-914
Number of pages5
JournalBiochemical and Biophysical Research Communications
Volume176
Issue number2
DOIs
Publication statusPublished - Apr 30 1991

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

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