After partial hepatectomy in rats, a ≈4-fold decrease in pp63 mRNA level was detected at 24h, but not at earlier time points. In mice, during liver cell proliferation induced by 1,4-bis[2-(3,5-dichloropyridyloxy) ]benzene and phenobarbital, pp63 transcript levels had a decrease of 40-50%. However, pp63 mRNA was 5-6 fold higher in murine hepatocellular tumors than in normal adult mouse liver.
|Number of pages||5|
|Journal||Biochemical and Biophysical Research Communications|
|Publication status||Published - Oct 31 1991|
ASJC Scopus subject areas
- Molecular Biology