Expression pattern of c-sis, c-fos and c-jun in human placenta and embryofetal organs

Daniela Rossi, Luca Del Giacco, Luisa Doneda, Umberto Nicolini, Barbara Acaia, Diana Brioschi, Lidia Larizza

Research output: Contribution to journalArticlepeer-review


The expression pattern of c-sis, c-fos and c-jun was investigated in placenta and embryofetal organ specimens from the first trimester. Northern analysis of the placentae showed c-sis transcripts and c-fos expression. Northern analysis of the same genes in embryofetal organs pointed to the brain as the only organ where consistent transcriptional activity could be observed. RT-PCR analysis of c-fos and c-jun in placentae, staged at four different time periods in pregnancy, allowed to detect the expected fragments in all cases. The same was true when c-fos and c-jun were analyzed at the 13th week of gestation in all the embryofetal organs.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalGynecologic and Obstetric Investigation
Issue number1
Publication statusPublished - Jul 1996


  • Human embryofetal organs
  • Human placenta
  • Northern analysis
  • Protooncogenes

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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