EXT-mutation analysis in Italian sporadic and hereditary osteochondromas

Maddalena Gigante; Maria G. Matera; Davide Seripa; Apollonia M. Izzo; Riccardo Venanzi; Aldo Giannotti; Maria C. Digilio; Carolina Gravina; Marzia Lazzari; Giovanni Monteleone; Maurizio Monteleone; Bruno Dallapiccola; Vito M. Fazio

doi:10.1002/1097-0215(20011120)95:6<378::AID-IJC1067>3.0.CO;2-F

EXT-mutation analysis in Italian sporadic and hereditary osteochondromas

Maddalena Gigante, Maria G. Matera, Davide Seripa, Apollonia M. Izzo, Riccardo Venanzi, Aldo Giannotti, Maria C. Digilio, Carolina Gravina, Marzia Lazzari, Giovanni Monteleone, Maurizio Monteleone, Bruno Dallapiccola, Vito M. Fazio

Research output: Contribution to journal › Article › peer-review

Abstract

Osteochondromas represent the largest group of benign tumors of bone. Multiple osteochondromatosis or hereditary multiple exostoses (EXT) is an autosomal dominant inherited disorder characterized by the presence of multiple benign cartilage-capped exostoses. EXT is genetically heterogeneous with at least 3 chromosomal loci: EXT1 (8q24.1), EXT2 (11p11-p13), and EXT3 (19p). In

Original language	English
Pages (from-to)	378-383
Number of pages	6
Journal	International Journal of Cancer
Volume	95
Issue number	6
DOIs	https://doi.org/10.1002/1097-0215(20011120)95:6<378::AID-IJC1067>3.0.CO;2-F
Publication status	Published - Nov 20 2001

Keywords

BcDNA: GH02288
Chondroma
Chondrosarcoma
DNA-SSCP
Drosophila
Exostoses
Exostosin
EXT
EXT1
EXT2
Germline mutations
Hereditary tumors
Mouse
PCR
Tumor suppressor genes

ASJC Scopus subject areas

Cancer Research
Oncology

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10.1002/1097-0215(20011120)95:6<378::AID-IJC1067>3.0.CO;2-F

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Gigante, M., Matera, M. G., Seripa, D., Izzo, A. M., Venanzi, R., Giannotti, A., Digilio, M. C., Gravina, C., Lazzari, M., Monteleone, G., Monteleone, M., Dallapiccola, B., & Fazio, V. M. (2001). EXT-mutation analysis in Italian sporadic and hereditary osteochondromas. International Journal of Cancer, 95(6), 378-383. https://doi.org/10.1002/1097-0215(20011120)95:6<378::AID-IJC1067>3.0.CO;2-F

Gigante, M, Matera, MG, Seripa, D, Izzo, AM, Venanzi, R, Giannotti, A, Digilio, MC, Gravina, C, Lazzari, M, Monteleone, G, Monteleone, M, Dallapiccola, B & Fazio, VM 2001, 'EXT-mutation analysis in Italian sporadic and hereditary osteochondromas', International Journal of Cancer, vol. 95, no. 6, pp. 378-383. https://doi.org/10.1002/1097-0215(20011120)95:6<378::AID-IJC1067>3.0.CO;2-F

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abstract = "Osteochondromas represent the largest group of benign tumors of bone. Multiple osteochondromatosis or hereditary multiple exostoses (EXT) is an autosomal dominant inherited disorder characterized by the presence of multiple benign cartilage-capped exostoses. EXT is genetically heterogeneous with at least 3 chromosomal loci: EXT1 (8q24.1), EXT2 (11p11-p13), and EXT3 (19p). In ",

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AU - Matera, Maria G.

AU - Seripa, Davide

AU - Izzo, Apollonia M.

AU - Venanzi, Riccardo

AU - Giannotti, Aldo

AU - Digilio, Maria C.

AU - Gravina, Carolina

AU - Lazzari, Marzia

AU - Monteleone, Giovanni

AU - Monteleone, Maurizio

AU - Dallapiccola, Bruno

AU - Fazio, Vito M.

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KW - BcDNA: GH02288

KW - Chondroma

KW - Chondrosarcoma

KW - DNA-SSCP

KW - Drosophila

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KW - Hereditary tumors

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KW - PCR

KW - Tumor suppressor genes

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EXT-mutation analysis in Italian sporadic and hereditary osteochondromas

Abstract

Keywords

ASJC Scopus subject areas

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