Extended resections for bronchogenic carcinoma invading the superior vena cava system

Lorenzo Spaggiari, Jean François Regnard, Pierre Magdeleinat, Bertrand Jauffret, Philippe Puyo, Philippe Levasseur

Research output: Contribution to journalArticlepeer-review

Abstract

Background. Extended resection of non-small-cell lung cancer (NSCLC) involving the superior vena cava (SVC) system is infrequently performed and oncologic benefits are still uncertain. Methods. From 1983 to 1996, 25 patients underwent resection of the SVC system for T4, NSCLC. Results. A total of 12 pneumonectomies (48%), ten lobectomies (40%), and three wedge resections (12%) were performed. Seven patients had complete resection of the SVC with graft interposition, 12 patients underwent tangential resection of the SVC, and 1 patient had a pericardial patch; 5 patients underwent resection of right innominate and subclavian veins without vessel reconstruction. The lymph node status was NO in 8 patients (32%), N1 in 3 (12%) and N2 in 14 patients (56%). Five patients (20%) underwent incomplete resection. Nine patients (36%) developed postoperative complications (36%) that were fatal in 3 patients (12%). At the completion of the study, 10 patients were still alive. The median survival was 11.5 months and the 5-year actuarial survival rate was 29%, with 4 patients alive at 5 years. Conclusions. The resection of the SVC system for direct involvement by T4, NSCLC can be performed in selected patients with an acceptable postoperative mortality. Even though no significant prognostic factors were observed, the patients who required a lobectomy with limited lymph node involvement seemed to benefit the most from surgery. (C) 2000 by The Society of Thoracic Surgeons.

Original languageEnglish
Pages (from-to)233-236
Number of pages4
JournalAnnals of Thoracic Surgery
Volume69
Issue number1
DOIs
Publication statusPublished - Jan 2000

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Fingerprint

Dive into the research topics of 'Extended resections for bronchogenic carcinoma invading the superior vena cava system'. Together they form a unique fingerprint.

Cite this