External quality assurance in cervical/vaginal cytology: Interlaboratory agreement in the Emilia-Romagna region of Italy

Valeria Cocchi; Catia Sintoni; Donata Carretti; Donatella Sama; Umberto Chiari; Valentina Segala; Anna Lucia Delazer; Nadia Grilli; Renata Papaleo; Carla Ghirardini; Lauro Bucchi

External quality assurance in cervical/vaginal cytology: Interlaboratory agreement in the Emilia-Romagna region of Italy

Valeria Cocchi, Catia Sintoni, Donata Carretti, Donatella Sama, Umberto Chiari, Valentina Segala, Anna Lucia Delazer, Nadia Grilli, Renata Papaleo, Carla Ghirardini, Lauro Bucchi

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori

Research output: Contribution to journal › Article › peer-review

Abstract

OBJECTIVE: To evaluate the diagnostic agreement between seven cervical/vaginal cytology laboratories participating in the first external quality assurance (EQA) scheme developed in Italy. STUDY DESIGN: Between 1991 and 1993, 110 cytologic smears were selected and classified by a committee and circulated and reported on by the laboratories according to the 1988 Bethesda System. Agreement was evaluated with the kappa statistic. Systematic disagreement was assessed by means of the Wilcoxon signed rank test. RESULTS: Interlaboratory kappa values varied between .01 and .29 (group score, .11) for sample adequacy and between .53 and .78 (group score, .67) for epithelial abnormalities. The lowest specific kappa values were observed for the three classes of sample adequacy (unsatisfactory, .07; less than optimal [LTO], .10; satisfactory [SAT], .14) and for the class of atypical cells of undetermined significance (ACUS), (.29). As compared with the study committee, 5/7 laboratories showed a systematic (P

Original language	English
Pages (from-to)	480-488
Number of pages	9
Journal	Acta Cytologica
Volume	40
Issue number	3
Publication status	Published - 1996

Keywords

cervix neoplasms
quality assurance, health care
vaginal neoplasms

ASJC Scopus subject areas

Anatomy
Cell Biology
Histology

Cite this

External quality assurance in cervical/vaginal cytology : Interlaboratory agreement in the Emilia-Romagna region of Italy. / Cocchi, Valeria; Sintoni, Catia; Carretti, Donata; Sama, Donatella; Chiari, Umberto; Segala, Valentina; Delazer, Anna Lucia; Grilli, Nadia; Papaleo, Renata; Ghirardini, Carla; Bucchi, Lauro.

In: Acta Cytologica, Vol. 40, No. 3, 1996, p. 480-488.

Research output: Contribution to journal › Article › peer-review

Cocchi, Valeria ; Sintoni, Catia ; Carretti, Donata ; Sama, Donatella ; Chiari, Umberto ; Segala, Valentina ; Delazer, Anna Lucia ; Grilli, Nadia ; Papaleo, Renata ; Ghirardini, Carla ; Bucchi, Lauro. / External quality assurance in cervical/vaginal cytology : Interlaboratory agreement in the Emilia-Romagna region of Italy. In: Acta Cytologica. 1996 ; Vol. 40, No. 3. pp. 480-488.

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abstract = "OBJECTIVE: To evaluate the diagnostic agreement between seven cervical/vaginal cytology laboratories participating in the first external quality assurance (EQA) scheme developed in Italy. STUDY DESIGN: Between 1991 and 1993, 110 cytologic smears were selected and classified by a committee and circulated and reported on by the laboratories according to the 1988 Bethesda System. Agreement was evaluated with the kappa statistic. Systematic disagreement was assessed by means of the Wilcoxon signed rank test. RESULTS: Interlaboratory kappa values varied between .01 and .29 (group score, .11) for sample adequacy and between .53 and .78 (group score, .67) for epithelial abnormalities. The lowest specific kappa values were observed for the three classes of sample adequacy (unsatisfactory, .07; less than optimal [LTO], .10; satisfactory [SAT], .14) and for the class of atypical cells of undetermined significance (ACUS), (.29). As compared with the study committee, 5/7 laboratories showed a systematic (P",

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AU - Sintoni, Catia

AU - Carretti, Donata

AU - Sama, Donatella

AU - Chiari, Umberto

AU - Segala, Valentina

AU - Delazer, Anna Lucia

AU - Grilli, Nadia

AU - Papaleo, Renata

AU - Ghirardini, Carla

AU - Bucchi, Lauro

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N2 - OBJECTIVE: To evaluate the diagnostic agreement between seven cervical/vaginal cytology laboratories participating in the first external quality assurance (EQA) scheme developed in Italy. STUDY DESIGN: Between 1991 and 1993, 110 cytologic smears were selected and classified by a committee and circulated and reported on by the laboratories according to the 1988 Bethesda System. Agreement was evaluated with the kappa statistic. Systematic disagreement was assessed by means of the Wilcoxon signed rank test. RESULTS: Interlaboratory kappa values varied between .01 and .29 (group score, .11) for sample adequacy and between .53 and .78 (group score, .67) for epithelial abnormalities. The lowest specific kappa values were observed for the three classes of sample adequacy (unsatisfactory, .07; less than optimal [LTO], .10; satisfactory [SAT], .14) and for the class of atypical cells of undetermined significance (ACUS), (.29). As compared with the study committee, 5/7 laboratories showed a systematic (P

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External quality assurance in cervical/vaginal cytology: Interlaboratory agreement in the Emilia-Romagna region of Italy

Abstract

Keywords

ASJC Scopus subject areas

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