Extracapillary glomerulonephritis and renal amyloidosis

Gabriella Moroni, Giovanni Banfi, Massimo Maccario, Marco Mereghetti, Claudio Ponticelli

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We report three patients with well-documented renal amyloidosis who developed rapidly progressive renal failure. Renal biopsies from all three patients showed crescentic glomerulonephritis imposed on renal amyloidosis. All patients were treated with intravenous high-dose methylprednisolone pulses combined with immunosuppressive agents and oral corticosteroids. Partial recovery of renal function was obtained in two patients. For the third patient, treatment had to be stopped after a few days because of a septic arthritis. Renal function continued to deteriorate, and the patient had to be placed on regular hemodialysis. We conclude that extracapillary glomerulonephritis may occasionally complicate a preexisting renal amyloidosis and may be reversible if recognized early and treated appropriately.

Original languageEnglish
Pages (from-to)695-699
Number of pages5
JournalAmerican Journal of Kidney Diseases
Issue number5
Publication statusPublished - Nov 1996


  • extracapillary glomerulonephritis
  • rapidly progressive renal failure
  • Renal amyloidosis

ASJC Scopus subject areas

  • Nephrology


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