Abstract
Rapidly progressive glomerulonephritis occurred in a woman with rheumatoid arthritis (RA) who had been treated with D-penicillamine for 3 months. Light microscopy study of the kidney showed severe glomerulonephritis with crescent formation in 50% of glomeruli and necrotizing vasculitis. Immunofluorescence revealed IgA and C3 granular deposits diffusely distributed along the capillary walls. The patient was treated with steroid 'pulse', antiplatelet agents and heparin and a partial recovery of renal function was observed after 2 months of anuria. This renal picture is unlike that reported in RA and a causative role for D-penicillamine is suggested.
Original language | English |
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Pages (from-to) | 56-60 |
Number of pages | 5 |
Journal | Nephron |
Volume | 33 |
Issue number | 1 |
Publication status | Published - 1983 |
ASJC Scopus subject areas
- Nephrology