Extracorporeal carbon dioxide removal (ECCO2R) in patients with acute respiratory failure

Andrea Morelli, Lorenzo Del Sorbo, Antonio Pesenti, V. Marco Ranieri, Eddy Fan

Research output: Contribution to journalReview article

Abstract

Purpose: To review the available knowledge related to the use of ECCO2R as adjuvant strategy to mechanical ventilation (MV) in various clinical settings of acute respiratory failure (ARF). Methods: Expert opinion and review of the literature. Results: ECCO2R may be a promising adjuvant therapeutic strategy for the management of patients with severe exacerbations of COPD and for the achievement of protective or ultra-protective ventilation in patients with ARDS without life-threatening hypoxemia. Given the observational nature of most of the available clinical data and differences in technical features and performances of current devices, the balance of risks and benefits for or against ECCO2R in such patient populations remains unclear Conclusions: ECCO2R is currently an experimental technique rather than an accepted therapeutic strategy in ARF—its safety and efficacy require confirmation in clinical trials.

Original languageEnglish
Pages (from-to)519-530
Number of pages12
JournalIntensive Care Medicine
Volume43
Issue number4
DOIs
Publication statusPublished - Apr 1 2017

Fingerprint

Carbon Dioxide
Respiratory Insufficiency
Expert Testimony
Artificial Respiration
Chronic Obstructive Pulmonary Disease
Ventilation
Clinical Trials
Safety
Equipment and Supplies
Therapeutics
Population
Hypoxia

Keywords

  • Adult
  • Artificial
  • Critical care
  • Extracorporeal CO removal
  • Intensive care units
  • Respiratory distress syndrome
  • Respiratory failure
  • Review
  • Ventilation

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Extracorporeal carbon dioxide removal (ECCO2R) in patients with acute respiratory failure. / Morelli, Andrea; Del Sorbo, Lorenzo; Pesenti, Antonio; Ranieri, V. Marco; Fan, Eddy.

In: Intensive Care Medicine, Vol. 43, No. 4, 01.04.2017, p. 519-530.

Research output: Contribution to journalReview article

Morelli, Andrea ; Del Sorbo, Lorenzo ; Pesenti, Antonio ; Ranieri, V. Marco ; Fan, Eddy. / Extracorporeal carbon dioxide removal (ECCO2R) in patients with acute respiratory failure. In: Intensive Care Medicine. 2017 ; Vol. 43, No. 4. pp. 519-530.
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