Extracorporeal photopheresis for paediatric patients experiencing graft-versus-host disease (GVHD)

Sergio Rutella, Caterina Giovanna Valentini, Stefano Ceccarelli, Maria Teresa Romano, Letizia P. Brescia, Giuseppe Maria Milano, Franco Locatelli

Research output: Contribution to journalArticlepeer-review

Abstract

Extracorporeal photopheresis (ECP) is broadly used in adults with cutaneous T-cell lymphoma, acute or chronic graft-versus-host disease (GVHD), rejection of solid organ transplants, and a variety of autoimmune, cell-mediated diseases. The predominant use of ECP in children and adolescents is for treating GVHD. Children pose specific challenges to ECP, due to their unique physiology and to patient's size. Herein, we will focus on current clinical trials with ECP in children with GVHD, with an emphasis on technical and clinical issues that are peculiar to the paediatric setting.

Original languageEnglish
Pages (from-to)340-348
Number of pages9
JournalTransfusion and Apheresis Science
Volume50
Issue number3
DOIs
Publication statusPublished - 2014

Keywords

  • Childhood leukemia
  • Graft-versus-host disease
  • Photopheresis
  • Solid organ transplantation.
  • Stem cell transplantation

ASJC Scopus subject areas

  • Hematology
  • Medicine(all)

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