Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints

Mahesh K B Parmar, Valter Torri, Lesley Stewart

Research output: Contribution to journalArticlepeer-review

Abstract

Meta-analyses aim to provide a full and comprehensive summary of related studies which have addressed a similar question. When the studies involve time to event (survival-type) data the most appropriate statistics to use are the log hazard ratio and its variance. However, these are not always explicitly presented for each study. In this paper a number of methods of extracting estimates of these statistics in a variety of situations are presented. Use of these methods should improve the efficiency and reliability of meta-analyses of the published literature with survival-type endpoints.

Original languageEnglish
Pages (from-to)2815-2834
Number of pages20
JournalStatistics in Medicine
Volume17
Issue number24
DOIs
Publication statusPublished - Dec 30 1998

ASJC Scopus subject areas

  • Epidemiology

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