Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints

Mahesh K B Parmar; Valter Torri; Lesley Stewart

doi:10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8

Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints

Mahesh K B Parmar, Valter Torri, Lesley Stewart

Istituto di Ricerche Farmacologiche "Mario Negri"

Research output: Contribution to journal › Article › peer-review

Abstract

Meta-analyses aim to provide a full and comprehensive summary of related studies which have addressed a similar question. When the studies involve time to event (survival-type) data the most appropriate statistics to use are the log hazard ratio and its variance. However, these are not always explicitly presented for each study. In this paper a number of methods of extracting estimates of these statistics in a variety of situations are presented. Use of these methods should improve the efficiency and reliability of meta-analyses of the published literature with survival-type endpoints.

Original language	English
Pages (from-to)	2815-2834
Number of pages	20
Journal	Statistics in Medicine
Volume	17
Issue number	24
DOIs	https://doi.org/10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8
Publication status	Published - Dec 30 1998

ASJC Scopus subject areas

Epidemiology

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10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8

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