Abstract
By exploiting the cross-reaction among the antigens associated with a pool of breast carcinomas, preselected according to their antigenic content, a CEA-like BCA, with a specific activity of 1400 U/μg, has been extracted, by means of 3M KCl, and partially purified by means of ConA Sepharose affinity chromatography and bioabsorption, employing, for the latter, a cross-reacting antiserum (anti CEA). The subsequent labelling, after Sephadex G-200 gel filtration, points out an immunological activity at the apex of the first peak versus anti CBC (or C.BCA) and anti CEA.
| Original language | English |
|---|---|
| Pages (from-to) | 8-14 |
| Number of pages | 7 |
| Journal | Bollettino dell'Istituto Sieroterapico Milanese |
| Volume | 61 |
| Issue number | 1 |
| Publication status | Published - 1982 |
ASJC Scopus subject areas
- Immunology
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Accinni, R., Bailo, M., Cavalca, V., Ferrara, R., Biancardi, C., & Bartorelli, A. (1982). Extraction and partial purification of a CEA-like BCA from a pool of pre-selected breast carcinomas. Bollettino dell'Istituto Sieroterapico Milanese, 61(1), 8-14.