Extradural motor cortex stimulation as a method to treat advanced Parkinson's disease: New perspective in geriatric medicine

Enrico Benvenuti, Francesca Cecchi, Angela Colombini, Guido Gori

Research output: Contribution to journalArticle

Abstract

Motor fluctuations not controlled by pharmacological therapy are often encountered in long-term Parkinson's disease (PD). Neurosurgery treatment represented by deep brain stimulation (DBS) was considered a valid alternative to pharmacological treatment. Unfortunately this method is most effective in patients under age of 70. Recently it has been suggested that extradural motor cortex stimulation (EMCS) could be a valid cost-effective alternative to DBS to control motor symptoms in patients affected by Parkinson's disease. The relevant non-invasive surgical technique makes this treatment particularly indicated in geriatric patients. Brain atrophy, cognitive impairment, psychiatric symptoms are not an absolute contraindication to the treatment. We submitted to EMCS an outpatient afferent to our geriatric department, a woman 68 yrs old. The patient showed an improvement of 35% as measured by the Unified Parkinson Disease Rating Scale (UPDRS) scale after the surgery. If our findings will be confirmed in larger series, a new dimension will be added to the treatment of PD.

Original languageEnglish
Pages (from-to)347-348
Number of pages2
JournalAging clinical and experimental research
Volume18
Issue number4
Publication statusPublished - Aug 2006

Fingerprint

Motor Cortex
Geriatrics
Parkinson Disease
Medicine
Deep Brain Stimulation
Therapeutics
Pharmacology
Neurosurgery
Atrophy
Psychiatry
Outpatients
Costs and Cost Analysis
Brain

Keywords

  • Extradural motor cortex stimulation (EMCS)
  • Parkinson's disease
  • Surgical treatment

ASJC Scopus subject areas

  • Ageing

Cite this

Extradural motor cortex stimulation as a method to treat advanced Parkinson's disease : New perspective in geriatric medicine. / Benvenuti, Enrico; Cecchi, Francesca; Colombini, Angela; Gori, Guido.

In: Aging clinical and experimental research, Vol. 18, No. 4, 08.2006, p. 347-348.

Research output: Contribution to journalArticle

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