TY - JOUR
T1 - Eyelid dermatitis
T2 - An evaluation of 447 patients
AU - Ayala, Fabio
AU - Fabbrocini, Gabriella
AU - Bacchilega, Roberto
AU - Berardesca, Enzo
AU - Caraffini, Stefano
AU - Corazza, Monica
AU - Flori, Maria Laura
AU - Francalanci, Stefano
AU - Guarrera, Marcella
AU - Lisi, Paolo
AU - Santucci, Baldassarre
AU - Schena, Donatella
AU - Suppa, Francesco
AU - Valsecchi, Rossano
AU - Vincenzi, Colombina
AU - Balato, Nicola
PY - 2003/6
Y1 - 2003/6
N2 - Backqround: Eyelids can be affected by various types of dermatitis that are often difficult to diagnose. Objective: The aim of the study was to establish some guidelines for a correct diagnosis. Methods: A total of 447 patients treated at 12 research units for eczema or other inflammatory dermatitis located on the eyelids were invited to complete a questionnaire. When necessary, patch tests with haptens of the standard series from Gruppo Italiano di Ricerca sulle Dermatiti da Contatto e Ambientali della Società Italiana di Dermatologia e Venereologia (SIDEV-GIRDCA) were performed. Results: Of the subjects studied, 50.2 % were diagnosed with allergic contact dermatitis (ACD); 20.9% were affected by irritant contact dermatitis (ICD), 13.5% by atopic dermatitis, 6.3% by seborrheic dermatitis, 6.5% by aspecific xerotic dermatitis, and 2.3% by psoriasis. Approximately 91% of all subjects reported an absence of familial atopy. A significant statistical association between diagnosis type and a personal history of atopy was evident (p <.000001, chi-square test). The results of gradual logistic regression models showed four-eyelid involvement as the main risk factor for ACD (odds ratio [OR] = 3.0; 95% CI, 1.1-8.1); with ICD, the main risk factor was the onset of symptoms at between 2 and 6 months (OR = 2.1; 95% CI, 1.1-4.0), whereas for atopic dermatitis, the main risk factors were the onset of symptoms later than 6 months and a personal history of atopy (OR = 4.9 and 3.6, respectively). Conclusion: Results suggest that many characteristics of the patients examined can be used for the differential diagnosis of palpebral eczematous dermatitis.
AB - Backqround: Eyelids can be affected by various types of dermatitis that are often difficult to diagnose. Objective: The aim of the study was to establish some guidelines for a correct diagnosis. Methods: A total of 447 patients treated at 12 research units for eczema or other inflammatory dermatitis located on the eyelids were invited to complete a questionnaire. When necessary, patch tests with haptens of the standard series from Gruppo Italiano di Ricerca sulle Dermatiti da Contatto e Ambientali della Società Italiana di Dermatologia e Venereologia (SIDEV-GIRDCA) were performed. Results: Of the subjects studied, 50.2 % were diagnosed with allergic contact dermatitis (ACD); 20.9% were affected by irritant contact dermatitis (ICD), 13.5% by atopic dermatitis, 6.3% by seborrheic dermatitis, 6.5% by aspecific xerotic dermatitis, and 2.3% by psoriasis. Approximately 91% of all subjects reported an absence of familial atopy. A significant statistical association between diagnosis type and a personal history of atopy was evident (p <.000001, chi-square test). The results of gradual logistic regression models showed four-eyelid involvement as the main risk factor for ACD (odds ratio [OR] = 3.0; 95% CI, 1.1-8.1); with ICD, the main risk factor was the onset of symptoms at between 2 and 6 months (OR = 2.1; 95% CI, 1.1-4.0), whereas for atopic dermatitis, the main risk factors were the onset of symptoms later than 6 months and a personal history of atopy (OR = 4.9 and 3.6, respectively). Conclusion: Results suggest that many characteristics of the patients examined can be used for the differential diagnosis of palpebral eczematous dermatitis.
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M3 - Article
C2 - 14749023
AN - SCOPUS:10744231846
VL - 14
SP - 69
EP - 74
JO - American Journal of Contact Dermatitis
JF - American Journal of Contact Dermatitis
SN - 1046-199X
IS - 2
ER -