Abstract
The present study was performed to assess the contribution of the Factor V Leiden mutation (FVL:FVQ506) to vascular thrombosis episodes and consequently to graft survival in liver transplanted patients. A consecutive series of 108 primary liver allograft adult recipients transplanted between January 1997 and June 2001, was analyzed. FV genotype polymorphism was determined by PCR-SSP technique. The results demonstrated that the six months and one year actuarial graft survivals of FVL mutation patient group (20 patients) were significantly lower than that of FV wild type cohort (88 patients) (42.8% vs. 78.1%, p
| Original language | Italian |
|---|---|
| Pages (from-to) | 411-419 |
| Number of pages | 9 |
| Journal | Trasfusione del Sangue |
| Volume | 47 |
| Issue number | 4 |
| Publication status | Published - 2002 |
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ASJC Scopus subject areas
- Hematology
- Immunology and Allergy
Cite this
Mutazione Leiden per il fattore V e perdita precoce dell'innesto nel trapianto di fegato. Casistica di un centro trapianti. / Barocci, Sergio; Fiordoro, Stefano; Santori, Gregorio; Morelli, Nicola; Antonelli, Paolo; Valente, Umberto; Andorno, Enzo; Nocera, Arcangelo.
In: Trasfusione del Sangue, Vol. 47, No. 4, 2002, p. 411-419.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mutazione Leiden per il fattore V e perdita precoce dell'innesto nel trapianto di fegato. Casistica di un centro trapianti
AU - Barocci, Sergio
AU - Fiordoro, Stefano
AU - Santori, Gregorio
AU - Morelli, Nicola
AU - Antonelli, Paolo
AU - Valente, Umberto
AU - Andorno, Enzo
AU - Nocera, Arcangelo
PY - 2002
Y1 - 2002
N2 - The present study was performed to assess the contribution of the Factor V Leiden mutation (FVL:FVQ506) to vascular thrombosis episodes and consequently to graft survival in liver transplanted patients. A consecutive series of 108 primary liver allograft adult recipients transplanted between January 1997 and June 2001, was analyzed. FV genotype polymorphism was determined by PCR-SSP technique. The results demonstrated that the six months and one year actuarial graft survivals of FVL mutation patient group (20 patients) were significantly lower than that of FV wild type cohort (88 patients) (42.8% vs. 78.1%, p
AB - The present study was performed to assess the contribution of the Factor V Leiden mutation (FVL:FVQ506) to vascular thrombosis episodes and consequently to graft survival in liver transplanted patients. A consecutive series of 108 primary liver allograft adult recipients transplanted between January 1997 and June 2001, was analyzed. FV genotype polymorphism was determined by PCR-SSP technique. The results demonstrated that the six months and one year actuarial graft survivals of FVL mutation patient group (20 patients) were significantly lower than that of FV wild type cohort (88 patients) (42.8% vs. 78.1%, p
KW - Actuarial graft survival
KW - Factor V Leiden
KW - Hepatic artery thrombosis
KW - Liver transplantation
KW - Polymerase chain reaction
UR - http://www.scopus.com/inward/record.url?scp=77950686301&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77950686301&partnerID=8YFLogxK
M3 - Articolo
AN - SCOPUS:77950686301
VL - 47
SP - 411
EP - 419
JO - Trasfusione del Sangue
JF - Trasfusione del Sangue
SN - 0041-1787
IS - 4
ER -