Mutazione Leiden per il fattore V e perdita precoce dell'innesto nel trapianto di fegato. Casistica di un centro trapianti

Translated title of the contribution: Factor V Leiden and early graft loss in liver transplanted patients: A single centre analysis

Sergio Barocci, Stefano Fiordoro, Gregorio Santori, Nicola Morelli, Paolo Antonelli, Umberto Valente, Enzo Andorno, Arcangelo Nocera

Research output: Contribution to journalArticle

Abstract

The present study was performed to assess the contribution of the Factor V Leiden mutation (FVL:FVQ506) to vascular thrombosis episodes and consequently to graft survival in liver transplanted patients. A consecutive series of 108 primary liver allograft adult recipients transplanted between January 1997 and June 2001, was analyzed. FV genotype polymorphism was determined by PCR-SSP technique. The results demonstrated that the six months and one year actuarial graft survivals of FVL mutation patient group (20 patients) were significantly lower than that of FV wild type cohort (88 patients) (42.8% vs. 78.1%, p

Translated title of the contributionFactor V Leiden and early graft loss in liver transplanted patients: A single centre analysis
Original languageItalian
Pages (from-to)411-419
Number of pages9
JournalTrasfusione del Sangue
Volume47
Issue number4
Publication statusPublished - 2002

ASJC Scopus subject areas

  • Hematology
  • Immunology and Allergy

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    Barocci, S., Fiordoro, S., Santori, G., Morelli, N., Antonelli, P., Valente, U., Andorno, E., & Nocera, A. (2002). Mutazione Leiden per il fattore V e perdita precoce dell'innesto nel trapianto di fegato. Casistica di un centro trapianti. Trasfusione del Sangue, 47(4), 411-419.