### Abstract

The reliability of transfer function (TF) estimates has been traditionally judged according to the threshold value of 0.5 in the magnitude squared coherence (MSC). However, other parameters affect the reliability as well, and low MSC values are often unavoidable in physiological systems. This study was devised 1) to assess by computer simulations the applicability of theoretical expressions for the error of TF estimates, 2) to provide error curves for TF estimates as a function of major experimental and analysis parameters and 3) to evaluate the fidelity of observed TF shapes with respect to expected ones when the MSC is low. Theoretical confidence intervals for the TF magnitude were found to be accurate enough to be used in practical analysis. Curves for the normalized bias and SD of TF estimates were derived, providing useful information for appropriate design of data collection and analysis. With an appropriate choice of analysis parameters the shape of observed TFs were found to be close to the expected ones even when the MSC is

Original language | English |
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Title of host publication | Computers in Cardiology |

Publisher | IEEE |

Pages | 639-642 |

Number of pages | 4 |

Publication status | Published - 1999 |

Event | The 26th Annual Meeting: Computers in Cardiology 1999 - Hannover, Ger Duration: Sep 26 1999 → Sep 29 1999 |

### Other

Other | The 26th Annual Meeting: Computers in Cardiology 1999 |
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City | Hannover, Ger |

Period | 9/26/99 → 9/29/99 |

### Fingerprint

### ASJC Scopus subject areas

- Software
- Cardiology and Cardiovascular Medicine

### Cite this

*Computers in Cardiology*(pp. 639-642). IEEE.

**Factors affecting the reliability of transfer function estimates of cardiovascular variability signals.** / Pinna, Gian Domenico; Maestri, R.; La Rovere, M. T.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

*Computers in Cardiology.*IEEE, pp. 639-642, The 26th Annual Meeting: Computers in Cardiology 1999, Hannover, Ger, 9/26/99.

}

TY - GEN

T1 - Factors affecting the reliability of transfer function estimates of cardiovascular variability signals

AU - Pinna, Gian Domenico

AU - Maestri, R.

AU - La Rovere, M. T.

PY - 1999

Y1 - 1999

N2 - The reliability of transfer function (TF) estimates has been traditionally judged according to the threshold value of 0.5 in the magnitude squared coherence (MSC). However, other parameters affect the reliability as well, and low MSC values are often unavoidable in physiological systems. This study was devised 1) to assess by computer simulations the applicability of theoretical expressions for the error of TF estimates, 2) to provide error curves for TF estimates as a function of major experimental and analysis parameters and 3) to evaluate the fidelity of observed TF shapes with respect to expected ones when the MSC is low. Theoretical confidence intervals for the TF magnitude were found to be accurate enough to be used in practical analysis. Curves for the normalized bias and SD of TF estimates were derived, providing useful information for appropriate design of data collection and analysis. With an appropriate choice of analysis parameters the shape of observed TFs were found to be close to the expected ones even when the MSC is

AB - The reliability of transfer function (TF) estimates has been traditionally judged according to the threshold value of 0.5 in the magnitude squared coherence (MSC). However, other parameters affect the reliability as well, and low MSC values are often unavoidable in physiological systems. This study was devised 1) to assess by computer simulations the applicability of theoretical expressions for the error of TF estimates, 2) to provide error curves for TF estimates as a function of major experimental and analysis parameters and 3) to evaluate the fidelity of observed TF shapes with respect to expected ones when the MSC is low. Theoretical confidence intervals for the TF magnitude were found to be accurate enough to be used in practical analysis. Curves for the normalized bias and SD of TF estimates were derived, providing useful information for appropriate design of data collection and analysis. With an appropriate choice of analysis parameters the shape of observed TFs were found to be close to the expected ones even when the MSC is

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M3 - Conference contribution

AN - SCOPUS:0033282525

SP - 639

EP - 642

BT - Computers in Cardiology

PB - IEEE

ER -