Factors associated with abruptio placentae in preterm deliveries

Arsenio Spinillo, Ezio Capuzzo, Laura Colonna, Laura Solerte, Sabrina Nicola, Secondo Guaschino

Research output: Contribution to journalArticlepeer-review


Objective. To evaluate risk factors associated with occurrence of abruptio placentae in preterm deliveries. Methods. Risk factors were evaluated in 55 consecutive index cases of abruptio placentae and 726 control patients delivered between 24-36 weeks' gestation. Results. In logistic regression analysis abruptio placentae was associated with a low number of antenatal visits, smoking in pregnancy, hypertension, intravenous drug abuse and a history of recent abdominal trauma. Among hypertensive disorders of pregnancy, preeclampsia superimposed on chronic hypertension was associated with the highest risk of premature placental separation. Finally, there was a significant trend relating duration of premature rupture of membranes with abruptio placentae (chi-square for trend = 3.93, p = 0.047). Conclusions. Several risk factors seem strongly associated with abruptio placentae in preterm deliveries; the presence of these risk factors should dictate intensive surveillance.

Original languageEnglish
Pages (from-to)307-312
Number of pages6
Issue number1
Publication statusPublished - 1992


  • Abruptio placentae
  • Preeclampsia
  • Premature rupture of membranes
  • Preterm delivery
  • Smoking

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology


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