Factors associated with anxiety in premature coronary artery disease patients: THC-PAC study

Seyed Hesameddin Abbasi, Seyed Ebrahim Kassaian, Saeed Sadeghian, Abbasali Karimi, Soheil Saadat, Flora Peyvandi, Arash Jalali, Tahereh Davarpasand, Shahin Akhondzadeh, Nazila Shahmansouri, Mohammad Ali Boroumand, Masoumeh Lotfi-Tokaldany, Maryam Amiri Abchouyeh, Farah Ayatollahzade Isfahani, Frits Rosendaal

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Anxiety may negatively affect the course of coronary artery disease (CAD). The aim of this study was to assess which factors are associated with anxiety in young adults with CAD. A cohort of individuals with premature coronary artery disease was formed between 2004-2011, as the Tehran Heart Center's Premature Coronary Atherosclerosis Cohort (THC-PAC) study. Patients (men ≤ 45-year-old, and women ≤ 55-year-old) were visited between March 2013 and February 2014. All participants were examined, and their demographic, clinical, and laboratory data were collected. Then, all participants filled in the Beck Anxiety Inventory. Logistic regression models were used to identifying factors related to anxiety in both sexes. During the study, 708 patients (mean [SD] age: 45.3 [5.8] y, men: 48.2%) were visited. Anxiety was present in 53.0% of participants (66.0% of women and 39.0% of men). The logistic regressions model showed that the associated factors for anxiety in men were opium usage (OR=1.89, 95%CI: 1.09-3.27), positive family history (OR=1.49, 95%CI: 0.94-2.35), and creatinine serum level (OR=1.17, 95%CI: 1.05-1.303); and in women were major adverse cardiac events (MACE) during follow-up (OR=2.30, 95%CI: 1.25-4.23), hypertension (OR=1.71, 95%CI: 1.07-2.73) and the duration of CAD (OR=0.99, 95%CI: 0.98-1.00). In premature CAD patients, the determinants of anxiety seem to be different in each sex. Opium usage, positive family history of CAD, and creatinine serum levels in men, and MACE, hypertension, and duration of CAD in women appear the relevant factors in this regard.

Original languageEnglish
Pages (from-to)261-269
Number of pages9
JournalActa Medica Iranica
Volume54
Issue number4
Publication statusPublished - 2016

Fingerprint

Coronary Artery Disease
Cohort Studies
Anxiety
Logistic Models
Opium
Creatinine
Hypertension
Serum
Young Adult
Demography
Equipment and Supplies

Keywords

  • Anxiety
  • Cohort studies
  • Coronary artery disease
  • Iran
  • Young adult

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Abbasi, S. H., Kassaian, S. E., Sadeghian, S., Karimi, A., Saadat, S., Peyvandi, F., ... Rosendaal, F. (2016). Factors associated with anxiety in premature coronary artery disease patients: THC-PAC study. Acta Medica Iranica, 54(4), 261-269.

Factors associated with anxiety in premature coronary artery disease patients : THC-PAC study. / Abbasi, Seyed Hesameddin; Kassaian, Seyed Ebrahim; Sadeghian, Saeed; Karimi, Abbasali; Saadat, Soheil; Peyvandi, Flora; Jalali, Arash; Davarpasand, Tahereh; Akhondzadeh, Shahin; Shahmansouri, Nazila; Boroumand, Mohammad Ali; Lotfi-Tokaldany, Masoumeh; Abchouyeh, Maryam Amiri; Isfahani, Farah Ayatollahzade; Rosendaal, Frits.

In: Acta Medica Iranica, Vol. 54, No. 4, 2016, p. 261-269.

Research output: Contribution to journalArticle

Abbasi, SH, Kassaian, SE, Sadeghian, S, Karimi, A, Saadat, S, Peyvandi, F, Jalali, A, Davarpasand, T, Akhondzadeh, S, Shahmansouri, N, Boroumand, MA, Lotfi-Tokaldany, M, Abchouyeh, MA, Isfahani, FA & Rosendaal, F 2016, 'Factors associated with anxiety in premature coronary artery disease patients: THC-PAC study', Acta Medica Iranica, vol. 54, no. 4, pp. 261-269.
Abbasi SH, Kassaian SE, Sadeghian S, Karimi A, Saadat S, Peyvandi F et al. Factors associated with anxiety in premature coronary artery disease patients: THC-PAC study. Acta Medica Iranica. 2016;54(4):261-269.
Abbasi, Seyed Hesameddin ; Kassaian, Seyed Ebrahim ; Sadeghian, Saeed ; Karimi, Abbasali ; Saadat, Soheil ; Peyvandi, Flora ; Jalali, Arash ; Davarpasand, Tahereh ; Akhondzadeh, Shahin ; Shahmansouri, Nazila ; Boroumand, Mohammad Ali ; Lotfi-Tokaldany, Masoumeh ; Abchouyeh, Maryam Amiri ; Isfahani, Farah Ayatollahzade ; Rosendaal, Frits. / Factors associated with anxiety in premature coronary artery disease patients : THC-PAC study. In: Acta Medica Iranica. 2016 ; Vol. 54, No. 4. pp. 261-269.
@article{377185fbc67b48a7945a7bf84ed8b299,
title = "Factors associated with anxiety in premature coronary artery disease patients: THC-PAC study",
abstract = "Background: Anxiety may negatively affect the course of coronary artery disease (CAD). The aim of this study was to assess which factors are associated with anxiety in young adults with CAD. A cohort of individuals with premature coronary artery disease was formed between 2004-2011, as the Tehran Heart Center's Premature Coronary Atherosclerosis Cohort (THC-PAC) study. Patients (men ≤ 45-year-old, and women ≤ 55-year-old) were visited between March 2013 and February 2014. All participants were examined, and their demographic, clinical, and laboratory data were collected. Then, all participants filled in the Beck Anxiety Inventory. Logistic regression models were used to identifying factors related to anxiety in both sexes. During the study, 708 patients (mean [SD] age: 45.3 [5.8] y, men: 48.2{\%}) were visited. Anxiety was present in 53.0{\%} of participants (66.0{\%} of women and 39.0{\%} of men). The logistic regressions model showed that the associated factors for anxiety in men were opium usage (OR=1.89, 95{\%}CI: 1.09-3.27), positive family history (OR=1.49, 95{\%}CI: 0.94-2.35), and creatinine serum level (OR=1.17, 95{\%}CI: 1.05-1.303); and in women were major adverse cardiac events (MACE) during follow-up (OR=2.30, 95{\%}CI: 1.25-4.23), hypertension (OR=1.71, 95{\%}CI: 1.07-2.73) and the duration of CAD (OR=0.99, 95{\%}CI: 0.98-1.00). In premature CAD patients, the determinants of anxiety seem to be different in each sex. Opium usage, positive family history of CAD, and creatinine serum levels in men, and MACE, hypertension, and duration of CAD in women appear the relevant factors in this regard.",
keywords = "Anxiety, Cohort studies, Coronary artery disease, Iran, Young adult",
author = "Abbasi, {Seyed Hesameddin} and Kassaian, {Seyed Ebrahim} and Saeed Sadeghian and Abbasali Karimi and Soheil Saadat and Flora Peyvandi and Arash Jalali and Tahereh Davarpasand and Shahin Akhondzadeh and Nazila Shahmansouri and Boroumand, {Mohammad Ali} and Masoumeh Lotfi-Tokaldany and Abchouyeh, {Maryam Amiri} and Isfahani, {Farah Ayatollahzade} and Frits Rosendaal",
year = "2016",
language = "English",
volume = "54",
pages = "261--269",
journal = "Acta Medica Iranica",
issn = "0044-6025",
publisher = "Teheran University of Medical Sciences",
number = "4",

}

TY - JOUR

T1 - Factors associated with anxiety in premature coronary artery disease patients

T2 - THC-PAC study

AU - Abbasi, Seyed Hesameddin

AU - Kassaian, Seyed Ebrahim

AU - Sadeghian, Saeed

AU - Karimi, Abbasali

AU - Saadat, Soheil

AU - Peyvandi, Flora

AU - Jalali, Arash

AU - Davarpasand, Tahereh

AU - Akhondzadeh, Shahin

AU - Shahmansouri, Nazila

AU - Boroumand, Mohammad Ali

AU - Lotfi-Tokaldany, Masoumeh

AU - Abchouyeh, Maryam Amiri

AU - Isfahani, Farah Ayatollahzade

AU - Rosendaal, Frits

PY - 2016

Y1 - 2016

N2 - Background: Anxiety may negatively affect the course of coronary artery disease (CAD). The aim of this study was to assess which factors are associated with anxiety in young adults with CAD. A cohort of individuals with premature coronary artery disease was formed between 2004-2011, as the Tehran Heart Center's Premature Coronary Atherosclerosis Cohort (THC-PAC) study. Patients (men ≤ 45-year-old, and women ≤ 55-year-old) were visited between March 2013 and February 2014. All participants were examined, and their demographic, clinical, and laboratory data were collected. Then, all participants filled in the Beck Anxiety Inventory. Logistic regression models were used to identifying factors related to anxiety in both sexes. During the study, 708 patients (mean [SD] age: 45.3 [5.8] y, men: 48.2%) were visited. Anxiety was present in 53.0% of participants (66.0% of women and 39.0% of men). The logistic regressions model showed that the associated factors for anxiety in men were opium usage (OR=1.89, 95%CI: 1.09-3.27), positive family history (OR=1.49, 95%CI: 0.94-2.35), and creatinine serum level (OR=1.17, 95%CI: 1.05-1.303); and in women were major adverse cardiac events (MACE) during follow-up (OR=2.30, 95%CI: 1.25-4.23), hypertension (OR=1.71, 95%CI: 1.07-2.73) and the duration of CAD (OR=0.99, 95%CI: 0.98-1.00). In premature CAD patients, the determinants of anxiety seem to be different in each sex. Opium usage, positive family history of CAD, and creatinine serum levels in men, and MACE, hypertension, and duration of CAD in women appear the relevant factors in this regard.

AB - Background: Anxiety may negatively affect the course of coronary artery disease (CAD). The aim of this study was to assess which factors are associated with anxiety in young adults with CAD. A cohort of individuals with premature coronary artery disease was formed between 2004-2011, as the Tehran Heart Center's Premature Coronary Atherosclerosis Cohort (THC-PAC) study. Patients (men ≤ 45-year-old, and women ≤ 55-year-old) were visited between March 2013 and February 2014. All participants were examined, and their demographic, clinical, and laboratory data were collected. Then, all participants filled in the Beck Anxiety Inventory. Logistic regression models were used to identifying factors related to anxiety in both sexes. During the study, 708 patients (mean [SD] age: 45.3 [5.8] y, men: 48.2%) were visited. Anxiety was present in 53.0% of participants (66.0% of women and 39.0% of men). The logistic regressions model showed that the associated factors for anxiety in men were opium usage (OR=1.89, 95%CI: 1.09-3.27), positive family history (OR=1.49, 95%CI: 0.94-2.35), and creatinine serum level (OR=1.17, 95%CI: 1.05-1.303); and in women were major adverse cardiac events (MACE) during follow-up (OR=2.30, 95%CI: 1.25-4.23), hypertension (OR=1.71, 95%CI: 1.07-2.73) and the duration of CAD (OR=0.99, 95%CI: 0.98-1.00). In premature CAD patients, the determinants of anxiety seem to be different in each sex. Opium usage, positive family history of CAD, and creatinine serum levels in men, and MACE, hypertension, and duration of CAD in women appear the relevant factors in this regard.

KW - Anxiety

KW - Cohort studies

KW - Coronary artery disease

KW - Iran

KW - Young adult

UR - http://www.scopus.com/inward/record.url?scp=84964311533&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84964311533&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84964311533

VL - 54

SP - 261

EP - 269

JO - Acta Medica Iranica

JF - Acta Medica Iranica

SN - 0044-6025

IS - 4

ER -