Abstract
Background: Anxiety may negatively affect the course of coronary artery disease (CAD). The aim of this study was to assess which factors are associated with anxiety in young adults with CAD. A cohort of individuals with premature coronary artery disease was formed between 2004-2011, as the Tehran Heart Center's Premature Coronary Atherosclerosis Cohort (THC-PAC) study. Patients (men ≤ 45-year-old, and women ≤ 55-year-old) were visited between March 2013 and February 2014. All participants were examined, and their demographic, clinical, and laboratory data were collected. Then, all participants filled in the Beck Anxiety Inventory. Logistic regression models were used to identifying factors related to anxiety in both sexes. During the study, 708 patients (mean [SD] age: 45.3 [5.8] y, men: 48.2%) were visited. Anxiety was present in 53.0% of participants (66.0% of women and 39.0% of men). The logistic regressions model showed that the associated factors for anxiety in men were opium usage (OR=1.89, 95%CI: 1.09-3.27), positive family history (OR=1.49, 95%CI: 0.94-2.35), and creatinine serum level (OR=1.17, 95%CI: 1.05-1.303); and in women were major adverse cardiac events (MACE) during follow-up (OR=2.30, 95%CI: 1.25-4.23), hypertension (OR=1.71, 95%CI: 1.07-2.73) and the duration of CAD (OR=0.99, 95%CI: 0.98-1.00). In premature CAD patients, the determinants of anxiety seem to be different in each sex. Opium usage, positive family history of CAD, and creatinine serum levels in men, and MACE, hypertension, and duration of CAD in women appear the relevant factors in this regard.
| Original language | English |
|---|---|
| Pages (from-to) | 261-269 |
| Number of pages | 9 |
| Journal | Acta Medica Iranica |
| Volume | 54 |
| Issue number | 4 |
| Publication status | Published - 2016 |
Fingerprint
Keywords
- Anxiety
- Cohort studies
- Coronary artery disease
- Iran
- Young adult
ASJC Scopus subject areas
- Medicine(all)
Cite this
Factors associated with anxiety in premature coronary artery disease patients : THC-PAC study. / Abbasi, Seyed Hesameddin; Kassaian, Seyed Ebrahim; Sadeghian, Saeed; Karimi, Abbasali; Saadat, Soheil; Peyvandi, Flora; Jalali, Arash; Davarpasand, Tahereh; Akhondzadeh, Shahin; Shahmansouri, Nazila; Boroumand, Mohammad Ali; Lotfi-Tokaldany, Masoumeh; Abchouyeh, Maryam Amiri; Isfahani, Farah Ayatollahzade; Rosendaal, Frits.
In: Acta Medica Iranica, Vol. 54, No. 4, 2016, p. 261-269.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Factors associated with anxiety in premature coronary artery disease patients
T2 - THC-PAC study
AU - Abbasi, Seyed Hesameddin
AU - Kassaian, Seyed Ebrahim
AU - Sadeghian, Saeed
AU - Karimi, Abbasali
AU - Saadat, Soheil
AU - Peyvandi, Flora
AU - Jalali, Arash
AU - Davarpasand, Tahereh
AU - Akhondzadeh, Shahin
AU - Shahmansouri, Nazila
AU - Boroumand, Mohammad Ali
AU - Lotfi-Tokaldany, Masoumeh
AU - Abchouyeh, Maryam Amiri
AU - Isfahani, Farah Ayatollahzade
AU - Rosendaal, Frits
PY - 2016
Y1 - 2016
N2 - Background: Anxiety may negatively affect the course of coronary artery disease (CAD). The aim of this study was to assess which factors are associated with anxiety in young adults with CAD. A cohort of individuals with premature coronary artery disease was formed between 2004-2011, as the Tehran Heart Center's Premature Coronary Atherosclerosis Cohort (THC-PAC) study. Patients (men ≤ 45-year-old, and women ≤ 55-year-old) were visited between March 2013 and February 2014. All participants were examined, and their demographic, clinical, and laboratory data were collected. Then, all participants filled in the Beck Anxiety Inventory. Logistic regression models were used to identifying factors related to anxiety in both sexes. During the study, 708 patients (mean [SD] age: 45.3 [5.8] y, men: 48.2%) were visited. Anxiety was present in 53.0% of participants (66.0% of women and 39.0% of men). The logistic regressions model showed that the associated factors for anxiety in men were opium usage (OR=1.89, 95%CI: 1.09-3.27), positive family history (OR=1.49, 95%CI: 0.94-2.35), and creatinine serum level (OR=1.17, 95%CI: 1.05-1.303); and in women were major adverse cardiac events (MACE) during follow-up (OR=2.30, 95%CI: 1.25-4.23), hypertension (OR=1.71, 95%CI: 1.07-2.73) and the duration of CAD (OR=0.99, 95%CI: 0.98-1.00). In premature CAD patients, the determinants of anxiety seem to be different in each sex. Opium usage, positive family history of CAD, and creatinine serum levels in men, and MACE, hypertension, and duration of CAD in women appear the relevant factors in this regard.
AB - Background: Anxiety may negatively affect the course of coronary artery disease (CAD). The aim of this study was to assess which factors are associated with anxiety in young adults with CAD. A cohort of individuals with premature coronary artery disease was formed between 2004-2011, as the Tehran Heart Center's Premature Coronary Atherosclerosis Cohort (THC-PAC) study. Patients (men ≤ 45-year-old, and women ≤ 55-year-old) were visited between March 2013 and February 2014. All participants were examined, and their demographic, clinical, and laboratory data were collected. Then, all participants filled in the Beck Anxiety Inventory. Logistic regression models were used to identifying factors related to anxiety in both sexes. During the study, 708 patients (mean [SD] age: 45.3 [5.8] y, men: 48.2%) were visited. Anxiety was present in 53.0% of participants (66.0% of women and 39.0% of men). The logistic regressions model showed that the associated factors for anxiety in men were opium usage (OR=1.89, 95%CI: 1.09-3.27), positive family history (OR=1.49, 95%CI: 0.94-2.35), and creatinine serum level (OR=1.17, 95%CI: 1.05-1.303); and in women were major adverse cardiac events (MACE) during follow-up (OR=2.30, 95%CI: 1.25-4.23), hypertension (OR=1.71, 95%CI: 1.07-2.73) and the duration of CAD (OR=0.99, 95%CI: 0.98-1.00). In premature CAD patients, the determinants of anxiety seem to be different in each sex. Opium usage, positive family history of CAD, and creatinine serum levels in men, and MACE, hypertension, and duration of CAD in women appear the relevant factors in this regard.
KW - Anxiety
KW - Cohort studies
KW - Coronary artery disease
KW - Iran
KW - Young adult
UR - http://www.scopus.com/inward/record.url?scp=84964311533&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84964311533&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:84964311533
VL - 54
SP - 261
EP - 269
JO - Acta Medica Iranica
JF - Acta Medica Iranica
SN - 0044-6025
IS - 4
ER -