Factors influencing the carotid baroreceptor response to pressure changes in a neck chamber

J. Ludbrook, G. Mancia, A. Ferrari, A. Zanchetti

Research output: Contribution to journalArticlepeer-review

Abstract

Transmission of pneumatic pressure from a neck chamber to the region of the carotid sinus is imperfect and asymmetric (86% of positive pressure, 64% of negative pressure). This has to be taken into account in the correct analysis of the carotid baroreceptor reflex. There is no evidence for a reduction in cerebral blood flow nor of carotid chemoreceptor stimulation in response to an increase in neck chamber pressure of about 45 mmHg. Thus it is likely that the pressor response to this maneuver is in fact due to reduction in carotid baroreceptor activity.

Original languageEnglish
Pages (from-to)347-349
Number of pages3
JournalClinical Science and Molecular Medicine
Volume51
Issue numberSup 3
Publication statusPublished - 1976

ASJC Scopus subject areas

  • Medicine(all)

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