Factors influencing the shape of the inspiratory flow

Edgardo D'Angelo, Edoardo Calderini, Andrea Wolfler, Matteo Pecchiari

Research output: Contribution to journalArticlepeer-review


An index (IS), quantitating the departure of the inspiratory flow profile (IFP) from the rectangular one, i.e. the optimal profile (IS=0), was computed from pneumotachograms recorded in 26 normal, anesthetized subjects breathing spontaneously through the endotracheal tube (ETT) or face mask (FM) with or without added resistances (R) and in 27 awake subjects breathing through the mouth and FM in the supine and seated posture at rest and during exercise (40 W) on a cycloergometer, through the nose and FM, and through the mouthpiece (MP). During anesthesia, IS decreased with R both while breathing through the ETT (ΔIS=-0.037±0.006 (SE); P

Original languageEnglish
Pages (from-to)211-219
Number of pages9
JournalRespiration Physiology
Issue number3
Publication statusPublished - 2001


  • Exercise, inspiratory flow profile
  • Inspiration, flow profile
  • Mammals, humans

ASJC Scopus subject areas

  • Physiology
  • Pulmonary and Respiratory Medicine


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