Failure of somatostatin to suppress thyrotropin releasing factor and luteinizing hormone releasing factor induced growth hormone release in acromegaly

G. Giustina, E. Reschini, M. Peracchi, L. Cantalamessa, F. Cavagnini, M. Pinto, P. Bulgheroni

Research output: Contribution to journalArticlepeer-review

Abstract

The effect of somatostatin on thyrotropin releasing factor or luteinizing hormone releasing factor induced growth hormone (GH) release was studied in 4 acromegalic patients. The increase in plasma GH induced by these nonspecific releasing factors still occurred despite somatostatin administration at a dose double the one sufficient to markedly decrease plasma GH levels in acromegalics and to completely suppress hypoglycemia or arginine induced GH release in normals.

Original languageEnglish
Pages (from-to)906-909
Number of pages4
JournalJournal of Clinical Endocrinology and Metabolism
Volume38
Issue number5
Publication statusPublished - 1974

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

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