False-positive galactomannan platelia Aspergillus test results for patients receiving piperacillin-tazobactam

Claudio Viscoli; Marco Machetti; Paola Cappellano; Barbara Bucci; Paolo Bruzzi; Maria Teresa Van Lint; Andrea Bacigalupo

doi:10.1086/382224

False-positive galactomannan platelia Aspergillus test results for patients receiving piperacillin-tazobactam

Claudio Viscoli, Marco Machetti, Paola Cappellano, Barbara Bucci, Paolo Bruzzi, Maria Teresa Van Lint, Andrea Bacigalupo

A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)

Research output: Contribution to journal › Article › peer-review

Abstract

At the bone marrow transplantation center of the San Martino Hospital (Genoa), we observed an increase in the rate of patients with positive Platelia Aspergillus (PA; Bio-Rad) test results, from 10% (38 of 386 patients) in the period from January 1999 through January 2003 to 36% (21 of 59 patients) in the period from February 2003 through May 2003. Positivity was significantly (P <.001) associated with the administration of piperacillin-tazobactam (PT) (17 [74%] of 23 patients who received PT had positive results vs. 4 [11%] of 36 who did not receive PT). Multivariate analysis found administration of PT (χ² = 34.7; P<.001) and underlying disease (χ² = 21.14; P <.001) to be associated with PA positivity. Of 15 PT batches tested, 12 had positive PA test results.

Original language	English
Pages (from-to)	913-916
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	38
Issue number	6
DOIs	https://doi.org/10.1086/382224
Publication status	Published - Mar 15 2004

ASJC Scopus subject areas

Immunology

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False-positive galactomannan platelia Aspergillus test results for patients receiving piperacillin-tazobactam. / Viscoli, Claudio; Machetti, Marco; Cappellano, Paola; Bucci, Barbara; Bruzzi, Paolo; Van Lint, Maria Teresa; Bacigalupo, Andrea.

In: Clinical Infectious Diseases, Vol. 38, No. 6, 15.03.2004, p. 913-916.

Research output: Contribution to journal › Article › peer-review

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abstract = "At the bone marrow transplantation center of the San Martino Hospital (Genoa), we observed an increase in the rate of patients with positive Platelia Aspergillus (PA; Bio-Rad) test results, from 10% (38 of 386 patients) in the period from January 1999 through January 2003 to 36% (21 of 59 patients) in the period from February 2003 through May 2003. Positivity was significantly (P <.001) associated with the administration of piperacillin-tazobactam (PT) (17 [74%] of 23 patients who received PT had positive results vs. 4 [11%] of 36 who did not receive PT). Multivariate analysis found administration of PT (χ2 = 34.7; P<.001) and underlying disease (χ2 = 21.14; P <.001) to be associated with PA positivity. Of 15 PT batches tested, 12 had positive PA test results.",

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AU - Bruzzi, Paolo

AU - Van Lint, Maria Teresa

AU - Bacigalupo, Andrea

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