Familial benign nonprogressive myoclonic epilepsies

Research output: Contribution to journalArticlepeer-review

Abstract

Work on the classification of epileptic syndromes is ongoing, and many syndromes are still under discussion. In particular, special difficulty still persists in correctly classifying epilepsies with myoclonic seizures. The existence of special familial epileptic syndromes primarily showing myoclonic features has been recently suggested on the basis of a clear pattern of inheritance or on the identification of new chromosomal genetic loci linked to the disease. These forms in development include familial infantile myoclonic epilepsy (FIME), benign adult familial myoclonic epilepsy (BAFME), or autosomal dominant cortical myoclonus and epilepsy (ADCME), and, maybe, adult-onset myoclonic epilepsy (AME). In the future, the identification of responsible genes and the protein products will contribute to our understanding of the molecular pathways of epileptogenesis and provide neurobiologic criteria for the classification of epilepsies, beyond the different phenotypic expression.

Original languageEnglish
Pages (from-to)37-40
Number of pages4
JournalEpilepsia
Volume50
Issue numberSUPPL. 5
DOIs
Publication statusPublished - May 2009

Keywords

  • ADCME
  • BAFME
  • Epilepsy
  • FIME
  • Genetics
  • Myoclonus

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Fingerprint Dive into the research topics of 'Familial benign nonprogressive myoclonic epilepsies'. Together they form a unique fingerprint.

Cite this