Familial Hypercholesterolemia in Cardiac Rehabilitation: a new field of interest. M. Ambrosetti, G. Malfatto, A.M. Cremona, M. Arca, P. Faggiano. Familial hypercholesterolemia (FH) is a frequently undiagnosed genetic disease characterized by substantial elevations of low-density lipoprotein cholesterol (LDL-C). The prevalence of heterozygous FH (HeFH) in the general population is 1:500 inhabitants, while the prevalence of homozygous FH (HoFH) is 1:1.000.000. If FH is not identified and aggressively treated at an early age, affected individuals have a 20-fold increased lifetime risk of coronary heart disease compared with the general population. This narrative review provide a concise overview of recommendations for diagnosis and treatment of adults and children with FH, and discuss the utility of considering FH as a comorbidity at the entry of Cardiac Rehabilitation programmes.
|Translated title of the contribution||Familial Hypercholesterolemia in Cardiac Rehabilitation: A new field of interest|
|Number of pages||6|
|Journal||Monaldi Archives for Chest Disease - Cardiac Series|
|Publication status||Published - Jun 1 2014|
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Pulmonary and Respiratory Medicine