Familial hypo-alpha-lipoproteinemia

Carlo Vergani, Giusy Bettale

Research output: Contribution to journalArticle

Abstract

A familial syndrome with hypo-alpha-lipoproteinemia is described. The affected propositus and his relatives have low levels of high density lipoprotein-cholesterol and apolipoprotein A, without any other lipid and lipoprotein abnormalities. Lipase activity and lecithinrcholesterol acyltransferase activity are also normal. A high prevalence of premature cardiac events was observed in this kindred, without any other established coronary risk factors present. The longevity analyses showed a shortening of life expectancy. The biochemical data and the pedigree are compatible with an autosomal dominant mode of inheritance.

Original languageEnglish
Pages (from-to)45-52
Number of pages8
JournalClinica Chimica Acta
Volume114
Issue number1
DOIs
Publication statusPublished - Jul 18 1981

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry

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